Varaico: Literature-Extracted Genetic Variants

Gene:LRP1
Variant:p.L256F
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LRP1

NM_002332.3:p.L256F

Associated Papers

Actionable Potentials of Less Frequently Mutated Genes in Colorectal Cancer and Their Roles in Precision Medicine.

Mohd Yunos RI et al.

Biomolecules, 2020

Association of Low-Density Lipoprotein Receptor-Related Protein 1 and Its rs1799986 Polymorphism With Mild Cognitive Impairment in Chinese Patients With Type 2 Diabetes.

Cao W et al.

Frontiers in Neuroscience, 2020

Association between LRP1 C766T polymorphism and Alzheimer's disease susceptibility: a meta-analysis.

Wang Y et al.

Scientific Reports, 2017

The LRP1 Gene Polymorphism is associated with Increased Risk of Metabolic Syndrome Prevalence in the Serbian Population.

Vučinić N et al.

Balkan Journal of Medical Genetics : Bjmg, 2017

A common polymorphism decreases LRP1 mRNA stability and is associated with increased plasma factor VIII levels.

Lee JD et al.

Biochimica Et Biophysica Acta. Molecular Basis of Disease, 2017

Systematic review and meta-analysis of genetic studies of late-life depression.

Tsang RS et al.

Neuroscience and Biobehavioral Reviews, 2017

APOE and APOC1 gene polymorphisms are associated with cognitive impairment progression in Chinese patients with late-onset Alzheimer's disease.

Zhou Q et al.

Neural Regeneration Research, 2014

LRP-1 polymorphism is associated with global and regional amyloid load in Alzheimer's Disease in humans in-vivo.

Grimmer T et al.

Neuroimage. Clinical, 2014

Apolipoprotein E genotype and LRP1 polymorphisms in patients with different clinical types of metachromatic leukodystrophy.

Ługowska A et al.

Gene, 2013

Association of polymorphisms in the LRP1 and A2M genes with Alzheimer's disease in the northern Chinese Han population.

Yuan Q et al.

Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia, 2013

Elevated factor VIII levels and risk of venous thrombosis.

Jenkins PV et al.

British Journal of Haematology, 2012

Preliminary evidence for an association between LRP-1 genotype and body mass index in humans.

Frazier-Wood AC et al.

Plos One, 2012

Capillary cerebral amyloid angiopathy identifies a distinct APOE epsilon4-associated subtype of sporadic Alzheimer's disease.

Thal DR et al.

Acta Neuropathologica, 2010

A megalin polymorphism associated with promoter activity and Alzheimer's disease risk.

Vargas T et al.

American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics, 2010

Association of the LRP1 gene and cognitive performance with amnestic mild cognitive impairment in elderly Chinese.

Shi YM et al.

International Psychogeriatrics, 2009

Non-apolipoprotein E and apolipoprotein E genetics of sporadic Alzheimer's disease.

Seripa D et al.

Ageing Research Reviews, 2009

LDL receptor-related protein 1: unique tissue-specific functions revealed by selective gene knockout studies.

Lillis AP et al.

Physiological Reviews, 2008

Genetics of Alzheimer's disease. A rapidly evolving field.

Serretti A et al.

Journal of Alzheimer's Disease : Jad, 2007

Low-density lipoprotein receptor-related protein 1 polymorphism 663 C > T affects clotting factor VIII activity and increases the risk of venous thromboembolism.

Vormittag R et al.

Journal of Thrombosis and Haemostasis : Jth, 2007

Association study of polymorphisms in LRP1, tau and 5-HTT genes and Alzheimer's disease in a sample of Colombian patients.

Forero DA et al.

Journal of Neural Transmission (vienna, Austria : 1996), 2006

[Meta-analysis of the association of the LRP C766T polymorphism with the risk of Alzheimer's disease].

Deng Y et al.

Yi Chuan = Hereditas, 2006

A 3'-UTR polymorphism in the oxidized LDL receptor 1 gene increases Abeta40 load as cerebral amyloid angiopathy in Alzheimer's disease.

Shi J et al.

Acta Neuropathologica, 2006

Differences in risk factors for dementia with neurodegenerative traits and for vascular dementia.

Wehr H et al.

Dementia and Geriatric Cognitive Disorders, 2006

Low-density lipoprotein receptor-related protein polymorphisms in patients with elevated factor VIII coagulant activity and venous thrombosis.

Cunningham N et al.

Blood Coagulation & Fibrinolysis : an International Journal in Haemostasis and Thrombosis, 2005

Association study and meta-analysis of low-density lipoprotein receptor related protein in Alzheimer's disease.

Pritchard A et al.

Neuroscience Letters, 2005

Genetic and functional characteristics of the human in vivo LRP1/A2MR receptor suggested as a risk marker for Alzheimer's disease and other complex (degenerative) diseases.

Gläser C et al.

Neuroscience Research, 2004

Association of the C766T polymorphism of the low-density lipoprotein receptor-related protein gene with Alzheimer's disease.

Kölsch H et al.

American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics, 2003

C766T low-density lipoprotein receptor-related protein 1 (LRP1) gene polymorphism and susceptibility to breast cancer.

Benes P et al.

Breast Cancer Research : Bcr, 2003

Genetic association of argyrophilic grain disease with polymorphisms in alpha-2 macroglobulin and low-density lipoprotein receptor-related protein genes.

Ghebremedhin E et al.

Neuropathology and Applied Neurobiology, 2002

The relationship among apolipoprotein(a) polymorphisms, the low-density lipoprotein receptor-related protein, and the very low density lipoprotein receptor genes, and plasma lipoprotein(A) concentration in the Czech population.

Benes P et al.

Human Biology, 2002

Pharmacogenomics for the treatment of dementia.

Cacabelos R

Annals of Medicine, 2002

The genetics of late-onset Alzheimer's disease.

Myers AJ et al.

Current Opinion in Neurology, 2001

Investigation of association of 13 polymorphisms in eight genes in southeastern African American Alzheimer disease patients as compared to age-matched controls.

Perry RT et al.

American Journal of Medical Genetics, 2001

Modulation of amyloid beta-protein clearance and Alzheimer's disease susceptibility by the LDL receptor-related protein pathway.

Kang DE et al.

The Journal of Clinical Investigation, 2000

Low density lipoprotein receptor-related protein gene polymorphisms and risk for late-onset Alzheimer's disease in a Japanese population.

Hatanaka Y et al.

Clinical Genetics, 2000

Confirmation of an association between a polymorphism in exon 3 of the low-density lipoprotein receptor-related protein gene and Alzheimer's disease.

Hollenbach E et al.

Neurology, 1998

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."