Associated Papers
LRP5: A Multifaceted Co-Receptor in Development, Disease, and Therapeutic Target.
Alrefaei AF
Cells, 2025
The genetic puzzle of rheumatoid arthritis: Causes, progression, and treatment.
Masoumi M et al.
Biochemistry and Biophysics Reports, 2025
The Relationship Between LRP-5 and LRP-6 Gene Mutations and Postmenopausal Type 2 Diabetes and Obesity.
Li J et al.
Clinical Medicine Insights. Endocrinology and Diabetes, 2025
Genetic variants in the LRP5 gene associated with gain and loss of bone mineral density.
Gorges DM et al.
In Silico Pharmacology, 2025
Fine-Scale Haplotype Mapping Reveals an Association of the FTO Gene with Osteoporosis and Fracture Risk in Postmenopausal Women.
Greere D et al.
Genes, 2024
Unique Splicing of Lrp5 in the Brain: A New Player in Neurodevelopment and Brain Maturation.
Luquero A et al.
International Journal of Molecular Sciences, 2024
Single nucleotide polymorphisms (rs3736228 and rs4988321) in low-density lipoprotein receptor-related protein-5 gene with predisposition to rheumatoid arthritis.
Zehra S et al.
Gene, 2023
Integrating Common Risk Factors with Polygenic Scores Improves the Prediction of Type 2 Diabetes.
Timasheva Y et al.
International Journal of Molecular Sciences, 2023
A Mild Case of Autosomal Recessive Osteopetrosis Masquerading as the Dominant Form Involving Homozygous Deep Intronic Variations in the CLCN7 Gene.
Hofstaetter JG et al.
Calcified Tissue International, 2022
Diagnostic yield of bone fragility gene panel sequencing in children and young adults referred for idiopathic primary osteoporosis at a single regional reference centre.
Rouleau C et al.
Bone Reports, 2022
A Survey of Multigenic Protein-Altering Variant Frequency in Familial Exudative Vitreo-Retinopathy (FEVR) Patients by Targeted Sequencing of Seven FEVR-Linked Genes.
Cicerone AP et al.
Genes, 2022
Why SNP rs3755955 is associated with human bone mineral density? A molecular and cellular study in bone cells.
He P et al.
Molecular and Cellular Biochemistry, 2022
Novel Loss-of-Function Mutations in NPR2 Cause Acromesomelic Dysplasia, Maroteaux Type.
Wu J et al.
Frontiers in Genetics, 2022
Fork-shaped mandibular incisors as a novel phenotype of LRP5-associated disorder.
Yamada M et al.
American Journal of Medical Genetics. Part A, 2021
Novel FZD4 and LRP5 mutations in a small cohort of patients with familial exudative vitreoretinopathy (FEVR).
Carrera W et al.
Ophthalmic Genetics, 2021
The association between vitamin D receptor FokI gene polymorphism and osteoporosis in postmenopausal women: a meta-analysis.
Wang S et al.
Climacteric : the Journal of the International Menopause Society, 2021
A novel statistical method for interpreting the pathogenicity of rare variants.
Wang J et al.
Genetics in Medicine : Official Journal of the American College of Medical Genetics, 2021
Associations of LRP5 and MTHFR Gene Variants with Osteoarthritis Prevalence in Elderly Women: A Japanese Cohort Survey Randomly Sampled from a Basic Resident Registry.
Nakano M et al.
Therapeutics and Clinical Risk Management, 2021
Association between rankl [RS9594759] and IL10 [RS1800896] Genes polymorphism and deciduous tooth eruption terms in Ukrainians born macrosomic.
Garmash OV et al.
Wiadomosci Lekarskie (warsaw, Poland : 1960), 2020
Genomic Medicine: Lessons Learned From Monogenic and Complex Bone Disorders.
Trajanoska K et al.
Frontiers in Endocrinology, 2020
Variations of Wnt/β-catenin pathway-related genes in susceptibility to knee osteoarthritis: A three-centre case-control study.
Huang Y et al.
Journal of Cellular and Molecular Medicine, 2019
The involvement of the canonical Wnt-signaling receptor LRP5 and LRP6 gene variants with ADHD and sexual dimorphism: Association study and meta-analysis.
Grünblatt E et al.
American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics, 2019
KDR (VEGFR2) Genetic Variants and Serum Levels in Patients with Rheumatoid Arthritis.
Paradowska-Gorycka A et al.
Biomolecules, 2019
Macular Hole Complicating Familial Exudative Vitreoretinopathy Due to LRP5 Mutation in an Adolescent.
Munier FL et al.
Ophthalmic Surgery, Lasers & Imaging Retina, 2019
LRP5, Bone Density, and Mechanical Stress: A Case Report and Literature Review.
Norwitz NG et al.
Frontiers in Endocrinology, 2019
Bone metabolism genes variation and response to bisphosphonate treatment in women with postmenopausal osteoporosis.
Marozik P et al.
Plos One, 2019
LRP5 gene polymorphisms and radiographic joint damage in rheumatoid arthritis patients.
Bernardes M et al.
Osteoporosis International : a Journal Established as Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the Usa, 2018
The low-density lipoprotein receptor-related protein 5 (LRP5) 4037C>T polymorphism: candidate for susceptibility to type 1 diabetes mellitus.
Souza KSC et al.
Archives of Endocrinology and Metabolism, 2018
Harnessing low-density lipoprotein receptor protein 6 (LRP6) genetic variation and Wnt signaling for innovative diagnostics in complex diseases.
Wang ZM et al.
The Pharmacogenomics Journal, 2018
Primary Osteoporosis in Young Adults: Genetic Basis and Identification of Novel Variants in Causal Genes.
Collet C et al.
Jbmr Plus, 2018
Non-homologous recombination between Alu and LINE-1 repeats results in a 91 kb deletion in MERTK causing severe retinitis pigmentosa.
Jonsson F et al.
Molecular Vision, 2018
Lack of Lrp5 Signaling in Osteoblasts Sensitizes Male Mice to Diet-Induced Disturbances in Glucose Metabolism.
Kim SP et al.
Endocrinology, 2017
Polymorphism in LRP5 (rs556442) is associated with higher TG levels in Iranian children.
Montazeri-Najafabady N et al.
Annals of Human Biology, 2017
Investigation of DNA repair-related SNPs underlying susceptibility to papillary thyroid carcinoma reveals MGMT as a novel candidate gene in Belarusian children exposed to radiation.
Lonjou C et al.
Bmc Cancer, 2017
Mutations in LRP5,FZD4, TSPAN12, NDP, ZNF408, or KIF11 Genes Account for 38.7% of Chinese Patients With Familial Exudative Vitreoretinopathy.
Rao FQ et al.
Investigative Ophthalmology & Visual Science, 2017
Functional relevance for associations between osteoporosis and genetic variants.
Liu K et al.
Plos One, 2017
Two novel susceptibility loci for non-small cell lung cancer map to low-density lipoprotein receptor-related protein 5.
Wang Y et al.
Oncology Letters, 2016
Severe osteoporosis with multiple spontaneous vertebral fractures in a young male carrying triple polymorphisms in the vitamin D receptor, collagen type 1, and low-density lipoprotein receptor-related peptide 5 genes.
Yavropoulou MP et al.
Hormones (athens, Greece), 2016
Low density lipoprotein receptor-related protein 5 gene polymorphisms and osteoporosis in Thai menopausal women.
Kitjaroentham A et al.
Journal of Negative Results in Biomedicine, 2016
Association of LRP5 Ala1330Val polymorphism with fracture risk: a meta-analysis.
Peng J et al.
Genetics and Molecular Research : Gmr, 2016
OPG, RANKL, and RANK gene polymorphisms and the bone mineral density response to alendronate therapy in postmenopausal Chinese women with osteoporosis or osteopenia.
Zheng H et al.
Pharmacogenetics and Genomics, 2016
Characterization of Disease-Associated Mutations in Human Transmembrane Proteins.
Molnár J et al.
Plos One, 2016
Associations of apolipoprotein E and low-density lipoprotein receptor-related protein 5 polymorphisms with dyslipidemia and generalized aggressive periodontitis in a Chinese population.
Gao H et al.
Journal of Periodontal Research, 2015
LRP receptor family member associated bone disease.
Lara-Castillo N et al.
Reviews in Endocrine & Metabolic Disorders, 2015
Atypical femoral fracture in osteoporosis pseudoglioma syndrome associated with two novel compound heterozygous mutations in LRP5.
Alonso N et al.
Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research, 2015
Polymorphism of LRP5 gene and emphysema severity are associated with osteoporosis in Japanese patients with or at risk for COPD.
Chubachi S et al.
Respirology (carlton, Vic.), 2015
Recent genetic discoveries in osteoporosis, sarcopenia and obesity.
Urano T et al.
Endocrine Journal, 2015
SOST polymorphisms and response to alendronate treatment in postmenopausal Chinese women with osteoporosis.
Zhou PR et al.
Pharmacogenomics, 2015
Genes Regulated by Vitamin D in Bone Cells Are Positively Selected in East Asians.
Arciero E et al.
Plos One, 2015