Associated Papers
Genetic complexity underlies clinical heterogeneity: YWTD β-propeller mutations and second-hit modifier mutations in LRP6-related tooth agenesis and ectodermal dysplasia in human.
Dong X et al.
Genes & Diseases, 2025
Genotype-phenotype analysis and functional study of three novel LRP6 variants in non-syndromic oligodontia.
Yuan Y et al.
Frontiers in Genetics, 2025
40534843 (PubMed )
Supplement: Table2.xlsx › Sheet2
Network expansion of genetic associations defines a pleiotropy map of human cell biology.
Barrio-Hernandez I et al.
Nature Genetics, 2023
36823319 (PubMed )
Supplement: EMS163741-supplement-Supplementary_Data_3.xlsx › ClinVar_evidence
Gastrointestinal symptoms in patients with isolated oligodontia and a Wnt gene mutation.
Ross JN et al.
Oral Diseases, 2023
Novel LRP6 Mutations Causing Non-Syndromic Oligodontia.
Lee Y et al.
Journal of Personalized Medicine, 2022
Synergistic Mutations of LRP6 and WNT10A in Familial Tooth Agenesis.
Chu KY et al.
Journal of Personalized Medicine, 2021
34834569 (PubMed )
Supplement: jpm-11-01217-s001.zip › jpm-1475506-supplementary.pdf
Rare phenotype: Hand preaxial polydactyly associated with LRP6-related tooth agenesis in humans.
Zhang L et al.
Npj Genomic Medicine, 2021
34759310 (PubMed )
Supplement: 41525_2021_262_MOESM1_ESM.pdf
A novel missense mutation of LRP6 identified by whole-exome sequencing in a Chinese family with non-syndromic tooth agenesis.
Wang H et al.
Orthodontics & Craniofacial Research, 2021
Investigation of a Novel LRP6 Variant Causing Autosomal-Dominant Tooth Agenesis.
Huang YX et al.
Frontiers in Genetics, 2021
Loss-of-Function Mutations in the WNT Co-receptor LRP6 Cause Autosomal-Dominant Oligodontia.
Massink MP et al.
American Journal of Human Genetics, 2015
Select a paper to view details