Varaico: Literature-Extracted Genetic Variants

Gene:LRP6
Variant:p.N81I
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LRP6

NM_002336.3:p.N81I

Associated Papers

Genetic variants in the LRP5 gene associated with gain and loss of bone mineral density.

Gorges DM et al.

In Silico Pharmacology, 2025

LRP6 High Bone Mass Characterized in Two Generations Harboring a Unique Mutation of Low-Density Lipoprotein Receptor-Related Protein 6.

Whyte MP et al.

Jbmr Plus, 2023

Crystal structures of the extracellular domain of LRP6 and its complex with DKK1.

Cheng Z et al.

Nature Structural & Molecular Biology, 2011

Genetic disorders of the LRP5-Wnt signalling pathway affecting the skeleton.

Koay MA et al.

Trends in Molecular Medicine, 2005

LDL receptor-related proteins 5 and 6 in Wnt/beta-catenin signaling: arrows point the way.

He X et al.

Development (cambridge, England), 2004

Six novel missense mutations in the LDL receptor-related protein 5 (LRP5) gene in different conditions with an increased bone density.

Van Wesenbeeck L et al.

American Journal of Human Genetics, 2003

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."