Varaico: Literature-Extracted Genetic Variants

Gene:LRRK2
Variant:p.T1343A
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LRRK2

NM_198578.4:p.T1343A

Associated Papers

Intramolecular feedback regulation of the LRRK2 Roc G domain by a LRRK2 kinase-dependent mechanism.

Gilsbach BK et al.

Elife, 2024

LRRK2 autophosphorylation enhances its GTPase activity.

Liu Z et al.

Faseb Journal : Official Publication of the Federation of American Societies for Experimental Biology, 2016

Differential effects of familial parkinson mutations in LRRK2 revealed by a systematic analysis of autophosphorylation.

Kamikawaji S et al.

Biochemistry, 2013

Autophosphorylation in the leucine-rich repeat kinase 2 (LRRK2) GTPase domain modifies kinase and GTP-binding activities.

Webber PJ et al.

Journal of Molecular Biology, 2011

The Parkinson's disease kinase LRRK2 autophosphorylates its GTPase domain at multiple sites.

Greggio E et al.

Biochemical and Biophysical Research Communications, 2009

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."