Varaico: Literature-Extracted Genetic Variants

Gene:LRRK2
Variant:p.T1348A
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LRRK2

NM_198578.4:p.T1348A

Associated Papers

LRRK2 autophosphorylation enhances its GTPase activity.

Liu Z et al.

Faseb Journal : Official Publication of the Federation of American Societies for Experimental Biology, 2016

Arsenite stress down-regulates phosphorylation and 14-3-3 binding of leucine-rich repeat kinase 2 (LRRK2), promoting self-association and cellular redistribution.

Mamais A et al.

The Journal of Biological Chemistry, 2014

Differential effects of familial parkinson mutations in LRRK2 revealed by a systematic analysis of autophosphorylation.

Kamikawaji S et al.

Biochemistry, 2013

Autophosphorylation in the leucine-rich repeat kinase 2 (LRRK2) GTPase domain modifies kinase and GTP-binding activities.

Webber PJ et al.

Journal of Molecular Biology, 2011

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."