Varaico: Literature-Extracted Genetic Variants

Gene:LRRK2
Variant:p.V1613A
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LRRK2

NM_198578.4:p.V1613A

Associated Papers

Impact of 100 LRRK2 variants linked to Parkinson's disease on kinase activity and microtubule binding.

Kalogeropulou AF et al.

The Biochemical Journal, 2022

Structure and nucleotide-induced conformational dynamics of the Chlorobium tepidum Roco protein.

Deyaert E et al.

The Biochemical Journal, 2019

Leucine-Rich Repeat Kinase (LRRK2) Genetics and Parkinson's Disease.

Monfrini E et al.

Advances in Neurobiology, 2017

Structural and functional in silico analysis of LRRK2 missense substitutions.

Cardona F et al.

Molecular Biology Reports, 2014

[Apoptosis of peripheral blood lymphocytes in patients with LRRK2-assoctated Parkinson's disease].

Usenko TS et al.

Tsitologiia, 2012

Association of LRRK2 exonic variants with susceptibility to Parkinson's disease: a case-control study.

Ross OA et al.

The Lancet. Neurology, 2011

Reduced content of α-synuclein in peripheral blood leukocytes of patients with LRRK2-associated Parkinson's disease.

Pchelina SN et al.

Bulletin of Experimental Biology and Medicine, 2011

[Clinical features of LRRK2-associated Parkinson's disease].

Pchelina SN et al.

Zhurnal Nevrologii I Psikhiatrii Imeni S.s. Korsakova, 2011

14-3-3 binding to LRRK2 is disrupted by multiple Parkinson's disease-associated mutations and regulates cytoplasmic localization.

Nichols RJ et al.

The Biochemical Journal, 2010

Genetic etiology of Parkinson disease associated with mutations in the SNCA, PARK2, PINK1, PARK7, and LRRK2 genes: a mutation update.

Nuytemans K et al.

Human Mutation, 2010

20506312 (PubMed )
Supplement: humu0031-0763-SD1.pdf

LRRK2 in Parkinson's disease: genetic and clinical studies from patients.

Kumari U et al.

The Febs Journal, 2009

LRRK2 gene variation and its contribution to Parkinson disease.

Paisán-Ruiz C

Human Mutation, 2009

Zeroing in on LRRK2-linked pathogenic mechanisms in Parkinson's disease.

Biskup S et al.

Biochimica Et Biophysica Acta, 2009

Molecular analyses of the LRRK2 gene in European and North African autosomal dominant Parkinson's disease.

Lesage S et al.

Journal of Medical Genetics, 2009

Parkinson's disease: from monogenic forms to genetic susceptibility factors.

Lesage S et al.

Human Molecular Genetics, 2009

Screening for LRRK2 mutations in patients with Parkinson's disease in Russia: identification of a novel LRRK2 variant.

Pchelina SN et al.

European Journal of Neurology, 2008

[Molecular basis of Parkinson's disease linked with mutations in the LRRK2 gene].

Pchelina SN et al.

Molekuliarnaia Biologiia, 0

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