Varaico: Literature-Extracted Genetic Variants

Gene:LTA
Variant:p.C13R
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LTA

NM_000595.4:p.C13R

Associated Papers

Frequency enrichment of coding variants in a French-Canadian founder population and its implication for inflammatory bowel diseases.

Bhérer C et al.

Medrxiv : the Preprint Server for Health Sciences, 2025

Whole exome sequencing reveals an FCGBP variant associated with spontaneous intraabdominal hemorrhage in severe acute pancreatitis.

Tang QY et al.

Imetaomics, 2025

41675706 (PubMed )
Supplement: IMO2-2-e52-s002.xlsx › 2D

Deep analysis of the major histocompatibility complex genetic associations using covariate analysis and haploblocks unravels new mechanisms for the molecular etiology of Elite Control in AIDS.

Rahmouni M et al.

Bmc Immunology, 2025

39762745 (PubMed )
Supplement: 12865_2024_680_MOESM2_ESM.xlsx › Supp-table5

Association of genetic variation in COL11A1 with adolescent idiopathic scoliosis.

Yu H et al.

Elife, 2024

38277211 (PubMed )
Supplement: elife-89762-supp1.xlsx › Variants

Association of genetic variation in COL11A1 with adolescent idiopathic scoliosis.

Yu H et al.

Biorxiv : the Preprint Server for Biology, 2023

37292598 (PubMed )
Supplement: media-1.xlsx › Variants

Prognostic significance of the genetic variant of lymphotoxin alpha (p.Thr60Asn) in egyptian patients with advanced hepatocellular carcinoma.

Alhelf M et al.

Molecular Biology Reports, 2023

Multitrait genome-wide analyses identify new susceptibility loci and candidate drugs to primary sclerosing cholangitis.

Han Y et al.

Nature Communications, 2023

36828809 (PubMed )
Supplement: 41467_2023_36678_MOESM12_ESM.xlsx › Table_S9

Deep resequencing identifies candidate functional genes in leprosy GWAS loci.

Fava VM et al.

Plos Neglected Tropical Diseases, 2021

34879060 (PubMed )
Supplement: pntd.0010029.s004.xlsx › S2_Table

Analysis of Lymphotoxin Alpha Expression in Human Retina and Generation of Expression Vectors to Functional Characterization of Polymorphisms in the Tumor Necrosis Factor Locus.

Usategui-Martín R et al.

Methods in Molecular Biology (clifton, N.j.), 2021

Variants of genes encoding TNF receptors and ligands and proteins regulating TNF activation in familial multiple sclerosis.

Torre-Fuentes L et al.

Cns Neuroscience & Therapeutics, 2020

32951330 (PubMed )
Supplement: CNS-26-1178-s002.xlsx › Hoja1

Mannose-binding lectin 2 gene polymorphisms and their association with tuberculosis in a Chinese population.

Zhang JX et al.

Infectious Diseases of Poverty, 2020

Multiple selective sweeps of ancient polymorphisms in and around LTα located in the MHC class III region on chromosome 6.

Campbell MC et al.

Bmc Evolutionary Biology, 2019

Genetic Susceptibility in Acute Pancreatitis: Genotyping of GSTM1, GSTT1, GSTP1, CASP7, CASP8, CASP9, CASP10, LTA, TNFRSF1B, and TP53 Gene Variants.

Dʼ Oliveira Martins F et al.

Pancreas, 2017

Functional characterization of rs2229094 (T>C) polymorphism in the tumor necrosis factor locus and lymphotoxin alpha expression in human retina: the Retina 4 project.

Pastor-Idoate S et al.

Clinical Ophthalmology (auckland, N.z.), 2017

Large-Scale Exome-wide Association Analysis Identifies Loci for White Blood Cell Traits and Pleiotropy with Immune-Mediated Diseases.

Tajuddin SM et al.

American Journal of Human Genetics, 2016

Genomic Characteristics of Genetic Creutzfeldt-Jakob Disease Patients with V180I Mutation and Associations with Other Neurodegenerative Disorders.

Lee SM et al.

Plos One, 2016

27341347 (PubMed )
Supplement: pone.0157540.s005.xlsx › Table_S5

Genetic variation in the TLR and NF-κB pathways and cervical and vulvar cancer risk: a population-based case-control study.

Bodelon C et al.

International Journal of Cancer, 2014

Next generation exome sequencing of paediatric inflammatory bowel disease patients identifies rare and novel variants in candidate genes.

Christodoulou K et al.

Gut, 2013

22543157 (PubMed )
Supplement: gutjnl-2011-301833-s1.pdf

Structure of tumor necrosis factor-alpha haploblocks in European populations.

Merino AM et al.

Immunogenetics, 2013

Investigation of lymphotoxin α genetic variants in migraine.

Oikari LE et al.

Gene, 2013

Four genetic polymorphisms of lymphotoxin-alpha gene and cancer risk: a systematic review and meta-analysis.

Huang Y et al.

Plos One, 2013

Gene polymorphisms and cytokine plasma levels as predictive factors of complications after cardiopulmonary bypass.

Jouan J et al.

The Journal of Thoracic and Cardiovascular Surgery, 2012

Innate immunity and non-Hodgkin's lymphoma (NHL) related genes in a nested case-control study for gastric cancer risk.

Park SK et al.

Plos One, 2012

23028900 (PubMed )
Supplement: pone.0045274.s001.xlsx › NHL

Genetic variation in proinflammatory cytokines IL6, IL6R, TNF-region, and TNFRSF1A and risk of breast cancer.

Madeleine MM et al.

Breast Cancer Research and Treatment, 2011

Haplotype-based association of four lymphotoxin-alpha gene polymorphisms with the risk of coronary artery disease in Han Chinese.

Liu Y et al.

The Tohoku Journal of Experimental Medicine, 2011

Candidate single nucleotide polymorphism markers for arsenic responsiveness of protein targets.

Isokpehi RD et al.

Bioinformatics and Biology Insights, 2010

20981267 (PubMed )
Supplement: BBI-4-supplementary.xls › SNPs3D_-_Substitutions_from_Cys

Obesity-dependent association of TNF-LTA locus with type 2 diabetes in North Indians.

Mahajan A et al.

Journal of Molecular Medicine (berlin, Germany), 2010

TNF, LTA and TGFB1 genotype distributions among acute graft-vs-host disease subsets after HLA-matched unrelated hematopoietic stem cell transplantation: a pilot study.

Shah R et al.

Tissue Antigens, 2009

Genome-wide analysis to predict protein sequence variations that change phosphorylation sites or their corresponding kinases.

Ryu GM et al.

Nucleic Acids Research, 2009

19139070 (PubMed )
Supplement: gkn1008_nar-01723-s-2008-File009.xls › TypeII_

Genetic variants in T helper cell type 1, 2 and 3 pathways and gastric cancer risk in a Polish population.

Mahajan R et al.

Japanese Journal of Clinical Oncology, 2008

Lymphotoxin-alpha polymorphisms and presence of cancer in 1,536 consecutive autopsy cases.

Takei K et al.

Bmc Cancer, 2008

The lymphotoxin Cys13Arg polymorphism and cognitive functioning in individuals with schizophrenia.

Dickerson F et al.

Schizophrenia Research, 2007

Functional variants in the lymphotoxin-alpha gene predict cardiovascular disease in dialysis patients.

Liu Y et al.

Journal of the American Society of Nephrology : Jasn, 2006

Genetic impact of TNF-beta on risk factors for coronary atherosclerosis.

Schulz S et al.

European Cytokine Network, 2006

Haplotype analysis of a 100 kb region spanning TNF-LTA identifies a polymorphism in the LTA promoter region that is associated with atopic asthma susceptibility in Japan.

Migita O et al.

Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology, 2005

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."