Varaico: Literature-Extracted Genetic Variants

Gene:LTA
Variant:p.T60N
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LTA

NM_000595.4:p.T60N

Associated Papers

Human iPSC-based breast cancer model identifies S100P-dependent cancer stemness induced by BRCA1 mutation.

Liu J et al.

Science Advances, 2025

40712032 (PubMed )
Supplement: sciadv.adi2370_tables_s8_and_s9.zip › adi2370_table_s9.xlsx › BRCA1-mutant_corrected_iPSC

Molecular Determinants of the Human Retinal Pigment Epithelium Cell Fate and Potential Pharmacogenomic Targets for Precision Medicine.

Zibetti C

International Journal of Molecular Sciences, 2025

40565279 (PubMed )
Supplement: ijms-26-05817-s001.zip › Table_S1_NGS_qc_and_WES_April2025_2_.xlsx › D2_hiPSCsvsPBMC_SNPs_InDels

Moroccan genome project: genomic insight into a North African population.

El Fahime E et al.

Communications Biology, 2025

Computational analysis of congenital heart disease associated SNPs: unveiling their impact on the gene regulatory system.

Vashisht S et al.

Bmc Genomics, 2025

39838281 (PubMed )
Supplement: 12864_2025_11232_MOESM4_ESM.xlsx › ClinVar_CHD-SNPs_uniq

Pharmacogenomic landscape of TNF inhibitors in the Middle Eastern Qatari population.

Jan Z et al.

Frontiers in Immunology, 2025

41346622 (PubMed )
Supplement: Table2.xlsx › Supplementary_Table_5

Genetic Determinants of Selenium Availability, Selenium-Response, and Risk of Polycystic Ovary Syndrome.

Sharma P et al.

Biological Trace Element Research, 2024

Whole-exome and whole-genome sequencing of 1064 individuals with type 1 diabetes reveals novel genes for diabetic kidney disease.

Haukka JK et al.

Diabetologia, 2024

Association of genetic variation in COL11A1 with adolescent idiopathic scoliosis.

Yu H et al.

Elife, 2024

38277211 (PubMed )
Supplement: elife-89762-supp1.xlsx › Variants

Targeting the non-coding genome and temozolomide signature enables CRISPR-mediated glioma oncolysis.

Tan IL et al.

Cell Reports, 2023

37917583 (PubMed )
Supplement: NIHMS1948186-supplement-2.xlsx › All-Pat-ClinVar_Coding

Association of genetic variation in COL11A1 with adolescent idiopathic scoliosis.

Yu H et al.

Biorxiv : the Preprint Server for Biology, 2023

37292598 (PubMed )
Supplement: media-1.xlsx › Variants

Prognostic significance of the genetic variant of lymphotoxin alpha (p.Thr60Asn) in egyptian patients with advanced hepatocellular carcinoma.

Alhelf M et al.

Molecular Biology Reports, 2023

Multitrait genome-wide analyses identify new susceptibility loci and candidate drugs to primary sclerosing cholangitis.

Han Y et al.

Nature Communications, 2023

36828809 (PubMed )
Supplement: 41467_2023_36678_MOESM12_ESM.xlsx › Table_S9

Genetic Factors in Familial Manifestation of Primary Mediastinal Large B-Cell Lymphoma over Two Generations.

Juskevicius D et al.

Pathobiology : Journal of Immunopathology, Molecular and Cellular Biology, 2023

Exome variants associated with asthma and allergy.

Wjst M

Scientific Reports, 2022

36470944 (PubMed )
Supplement: 41598_2022_24960_MOESM1_ESM.pdf

Type 2 Diabetes-Related Variants Influence the Risk of Developing Prostate Cancer: A Population-Based Case-Control Study and Meta-Analysis.

Sánchez-Maldonado JM et al.

Cancers, 2022

Deep resequencing identifies candidate functional genes in leprosy GWAS loci.

Fava VM et al.

Plos Neglected Tropical Diseases, 2021

34879060 (PubMed )
Supplement: pntd.0010029.s004.xlsx › S2_Table

Variants of genes encoding TNF receptors and ligands and proteins regulating TNF activation in familial multiple sclerosis.

Torre-Fuentes L et al.

Cns Neuroscience & Therapeutics, 2020

32951330 (PubMed )
Supplement: CNS-26-1178-s002.xlsx › Hoja1

Currently favored sampling practices for tumor sequencing can produce optimal results in the clinical setting.

Pongor LS et al.

Scientific Reports, 2020

32873813 (PubMed )
Supplement: 41598_2020_71382_MOESM6_ESM.xlsx › Hypermutating

Mannose-binding lectin 2 gene polymorphisms and their association with tuberculosis in a Chinese population.

Zhang JX et al.

Infectious Diseases of Poverty, 2020

Multiple selective sweeps of ancient polymorphisms in and around LTα located in the MHC class III region on chromosome 6.

Campbell MC et al.

Bmc Evolutionary Biology, 2019

Genetic Studies of Inflammatory Bowel Disease-Focusing on Asian Patients.

Park SC et al.

Cells, 2019

Genetic and Epigenetic Studies in Diabetic Kidney Disease.

Gu HF

Frontiers in Genetics, 2019

Whole exome sequencing in three families segregating a pediatric case of sarcoidosis.

Calender A et al.

Bmc Medical Genomics, 2018

29510755 (PubMed )
Supplement: 12920_2018_338_MOESM6_ESM.xlsx › Feuil3

Exome-wide analyses identify low-frequency variant in CYP26B1 and additional coding variants associated with esophageal squamous cell carcinoma.

Chang J et al.

Nature Genetics, 2018

How gene polymorphisms can influence clinical response and toxicity following R-CHOP therapy in patients with diffuse large B cell lymphoma.

Falduto A et al.

Blood Reviews, 2017

Exome-wide Association Study Identifies CLEC3B Missense Variant p.S106G as Being Associated With Extreme Longevity in East Asian Populations.

Tanisawa K et al.

The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences, 2017

27154906 (PubMed )
Supplement: glw074_suppl_20160228_jgbs_2015_218r1_supplemantary_tables.xlsx › Table_S1

Genetic Susceptibility in Acute Pancreatitis: Genotyping of GSTM1, GSTT1, GSTP1, CASP7, CASP8, CASP9, CASP10, LTA, TNFRSF1B, and TP53 Gene Variants.

Dʼ Oliveira Martins F et al.

Pancreas, 2017

A common variant within the HNF1B gene is associated with overall survival of multiple myeloma patients: results from the IMMEnSE consortium and meta-analysis.

Ríos-Tamayo R et al.

Oncotarget, 2016

Glycidamide genotoxicity modulated by Caspases genes polymorphisms.

de Lima JP et al.

Toxicology in Vitro : an International Journal Published in Association With Bibra, 2016

Type 2 diabetes-related variants influence the risk of developing multiple myeloma: results from the IMMEnSE consortium.

Ríos R et al.

Endocrine-related Cancer, 2015

Cytokine gene polymorphisms in obstructive sleep apnoea/hypopnoea syndrome.

Bielicki P et al.

Sleep Medicine, 2015

SNP screening of central MHC-identified HLA-DMB as a candidate susceptibility gene for HIV-related Kaposi's sarcoma.

Aissani B et al.

Genes and Immunity, 2014

GWAS-identified common variants for obesity are not associated with the risk of developing colorectal cancer.

Sainz J et al.

Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology, 2014

Genome-wide survey of interindividual differences of RNA stability in human lymphoblastoid cell lines.

Duan J et al.

Scientific Reports, 2013

23422947 (PubMed )
Supplement: srep01318-s2.xls › S7

Can certain genotypes predispose to poor asthma control in children? A pharmacogenetic study of 9 candidate genes in children with difficult asthma.

Almomani B et al.

Plos One, 2013

Association between genetic variants in the tumour necrosis factor/lymphotoxin α/lymphotoxin β locus and primary Sjogren's syndrome in Scandinavian samples.

Bolstad AI et al.

Annals of the Rheumatic Diseases, 2012

TLR-3 polymorphism is an independent prognostic marker for stage II colorectal cancer.

Castro FA et al.

European Journal of Cancer (oxford, England : 1990), 2011

Polymorphisms in apoptosis-related genes and survival of patients with early-stage non-small-cell lung cancer.

Lee EB et al.

Annals of Surgical Oncology, 2010

A genetic association study of maternal and fetal candidate genes that predispose to preterm prelabor rupture of membranes (PROM).

Romero R et al.

American Journal of Obstetrics and Gynecology, 2010

Genetic association of Toll-like-receptor 4 and tumor necrosis factor-alpha polymorphisms with Plasmodium falciparum blood infection levels.

Basu M et al.

Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases, 2010

Large-scale association analysis of TNF/LTA gene region polymorphisms in type 2 diabetes.

Boraska V et al.

Bmc Medical Genetics, 2010

TNF superfamily gene polymorphism as prognostic factor in early breast cancer.

Jung JH et al.

Journal of Cancer Research and Clinical Oncology, 2010

Obesity-dependent association of TNF-LTA locus with type 2 diabetes in North Indians.

Mahajan A et al.

Journal of Molecular Medicine (berlin, Germany), 2010

Association of HLA-DRB1, interleukin-6 and cyclin D1 polymorphisms with cervical cancer in the Swedish population--a candidate gene approach.

Castro FA et al.

International Journal of Cancer, 2009

Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity.

Thorleifsson G et al.

Nature Genetics, 2009

Lymphotoxin-alpha polymorphisms and presence of cancer in 1,536 consecutive autopsy cases.

Takei K et al.

Bmc Cancer, 2008

Association between LTA, TNF and AGER polymorphisms and late diabetic complications.

Lindholm E et al.

Plos One, 2008

Association of TNFSF15 with Crohn's disease in Koreans.

Yang SK et al.

The American Journal of Gastroenterology, 2008

A functional polymorphism of the TNF-alpha gene that is associated with type 2 DM.

Susa S et al.

Biochemical and Biophysical Research Communications, 2008

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."