Associated Papers
Retinylidene chromophore hydrolysis from mammalian visual and non-visual opsins.
Hong JD et al.
The Journal of Biological Chemistry, 2024
High-Accuracy Prediction of Stabilizing Surface Mutations to the Three-Helix Bundle, UBA(1), with EmCAST.
Rothfuss MT et al.
Journal of the American Chemical Society, 2023
OPUS-Mut: Studying the Effect of Protein Mutation through Side-Chain Modeling.
Xu G et al.
Journal of Chemical Theory and Computation, 2023
Structure of the metastatic factor P-Rex1 reveals a two-layered autoinhibitory mechanism.
Chang YG et al.
Nature Structural & Molecular Biology, 2022
A strategy for proline and glycine mutations to proteins with alchemical free energy calculations.
Hayes RL et al.
Journal of Computational Chemistry, 2021
The pKa values of the catalytic residues in the retaining glycoside hydrolase T26H mutant of T4 lysozyme.
Brockerman JA et al.
Protein Science : a Publication of the Protein Society, 2019
Mechanisms for Benzene Dissociation through the Excited State of T4 Lysozyme L99A Mutant.
Feher VA et al.
Biophysical Journal, 2019
PON-tstab: Protein Variant Stability Predictor. Importance of Training Data Quality.
Yang Y et al.
International Journal of Molecular Sciences, 2018
Structural Connection between Activation Microswitch and Allosteric Sodium Site in GPCR Signaling.
White KL et al.
Structure (london, England : 1993), 2018
Prediction of protein relative enthalpic stability from molecular dynamics simulations of the folded and unfolded states.
Dadarlat VM et al.
Biophysical Journal, 2012
Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist.
Haga K et al.
Nature, 2012
Alanine-scanning mutagenesis of the beta-sheet region of phage T4 lysozyme suggests that tertiary context has a dominant effect on beta-sheet formation.
He MM et al.
Protein Science : a Publication of the Protein Society, 2004
A helix initiation signal in T4 lysozyme identified by polyalanine mutagenesis.
Zhang XJ et al.
Biophysical Chemistry, 2002
Predicting the structure of protein cavities created by mutation.
Machicado C et al.
Protein Engineering, 2002
Theoretical studies of the response of a protein structure to cavity-creating mutations.
Lee J et al.
Biophysical Journal, 2000
Structural analysis of a non-contiguous second-site revertant in T4 lysozyme shows that increasing the rigidity of a protein can enhance its stability.
Wray JW et al.
Journal of Molecular Biology, 1999
Context-dependent protein stabilization by methionine-to-leucine substitution shown in T4 lysozyme.
Lipscomb LA et al.
Protein Science : a Publication of the Protein Society, 1998
Hydrophobic core repacking and aromatic-aromatic interaction in the thermostable mutant of T4 lysozyme Ser 117-->Phe.
Anderson DE et al.
Protein Science : a Publication of the Protein Society, 1993
Design and structural analysis of alternative hydrophobic core packing arrangements in bacteriophage T4 lysozyme.
Hurley JH et al.
Journal of Molecular Biology, 1992
Differential scanning calorimetric study of the thermal unfolding of mutant forms of phage T4 lysozyme.
Hu CQ et al.
Biochemistry, 1992
Structural and thermodynamic consequences of burying a charged residue within the hydrophobic core of T4 lysozyme.
Dao-pin S et al.
Biochemistry, 1991
Contributions of engineered surface salt bridges to the stability of T4 lysozyme determined by directed mutagenesis.
Sun DP et al.
Biochemistry, 1991
Second-site revertants of an inactive T4 lysozyme mutant restore activity by restructuring the active site cleft.
Poteete AR et al.
Biochemistry, 1991
Unpaired cysteine-54 interferes with the ability of an engineered disulfide to stabilize T4 lysozyme.
Perry LJ et al.
Biochemistry, 1986