Associated Papers
CCDC50 mediates the clearance of protein aggregates to prevent cellular proteotoxicity.
Ye Y et al.
Autophagy, 2024
The autophagy adaptor TRIAD3A promotes tau fibrillation by nested phase separation.
Zhou J et al.
Nature Cell Biology, 2024
Mast cell secretory granule fusion with amphisomes coordinates their homotypic fusion and release of exosomes.
Omari S et al.
Cell Reports, 2024
Development of new tools to study membrane-anchored mammalian Atg8 proteins.
Park SW et al.
Autophagy, 2023
The Autophagy Receptor TAX1BP1 (T6BP) improves antigen presentation by MHC-II molecules.
Sarango G et al.
Embo Reports, 2022
CCT2 is an aggrephagy receptor for clearance of solid protein aggregates.
Ma X et al.
Cell, 2022
The functions of Atg8-family proteins in autophagy and cancer: linked or unrelated?
Jacquet M et al.
Autophagy, 2021
DNA-dependent protein kinase regulates lysosomal AMP-dependent protein kinase activation and autophagy.
Puustinen P et al.
Autophagy, 2020
LC3 lipidation is essential for TFEB activation during the lysosomal damage response to kidney injury.
Nakamura S et al.
Nature Cell Biology, 2020
Inhibition of autophagy curtails visual loss in a model of autosomal dominant optic atrophy.
Zaninello M et al.
Nature Communications, 2020
Redundancy of human ATG4 protease isoforms in autophagy and LC3/GABARAP processing revealed in cells.
Agrotis A et al.
Autophagy, 2019
A cancer associated somatic mutation in LC3B attenuates its binding to E1-like ATG7 protein and subsequent lipidation.
Nuta GC et al.
Autophagy, 2019
Autophagic cell death restricts chromosomal instability during replicative crisis.
Nassour J et al.
Nature, 2019
GABARAPL1 tumor suppressive function is independent of its conjugation to autophagosomes in MCF-7 breast cancer cells.
Poillet-Perez L et al.
Oncotarget, 2017
Mutation-Structure-Function Relationship Based Integrated Strategy Reveals the Potential Impact of Deleterious Missense Mutations in Autophagy Related Proteins on Hepatocellular Carcinoma (HCC): A Comprehensive Informatics Approach.
Awan FM et al.
International Journal of Molecular Sciences, 2017
Regulation of autophagy by mitochondrial phospholipids in health and diseases.
Hsu P et al.
Biochimica Et Biophysica Acta. Molecular and Cell Biology of Lipids, 2017
Excess sphingomyelin disturbs ATG9A trafficking and autophagosome closure.
Corcelle-Termeau E et al.
Autophagy, 2016
A non-conserved miRNA regulates lysosomal function and impacts on a human lysosomal storage disorder.
Frankel LB et al.
Nature Communications, 2014
Internalized gap junctions are degraded by autophagy.
Fong JT et al.
Autophagy, 2012
TLR4-mediated autophagy in macrophages is a p62-dependent type of selective autophagy of aggresome-like induced structures (ALIS).
Fujita K et al.
Autophagy, 2011
Acetylation targets mutant huntingtin to autophagosomes for degradation.
Jeong H et al.
Cell, 2009
The N-terminus and Phe52 residue of LC3 recruit p62/SQSTM1 into autophagosomes.
Shvets E et al.
Journal of Cell Science, 2008
Post-translational modifications of three members of the human MAP1LC3 family and detection of a novel type of modification for MAP1LC3B.
He H et al.
The Journal of Biological Chemistry, 2003