Varaico: Literature-Extracted Genetic Variants

Gene:MAP2K1
Variant:p.L37P
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MAP2K1

NM_002755.4:p.L37P

Associated Papers

RAF-independent MEK mutations drive refractory histiocytic neoplasms but respond to ERK inhibition.

Diamond EL et al.

Cancer Cell, 2026

Concurrence of a kinase-dead BRAF and an oncogenic KRAS gain-of-function mutation in juvenile xanthogranuloma.

Seidel MG et al.

Pediatric Blood & Cancer, 2023

Activating mutations in CSF1R and additional receptor tyrosine kinases in histiocytic neoplasms.

Durham BH et al.

Nature Medicine, 2019

31768065 (PubMed )
Supplement: NIHMS1541330-supplement-1.pdf

Rosai-Dorfman Disease Harboring an Activating KRAS K117N Missense Mutation.

Shanmugam V et al.

Head and Neck Pathology, 2016

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."