Varaico: Literature-Extracted Genetic Variants

Gene:MAP2K1
Variant:p.K57_E62del0
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MAP2K1

NM_002755.4:p.K57_E62del0

Associated Papers

Personalized and Tumor Informed Circulating Tumor DNA Assay for Molecular Residual Disease Monitoring of Solid Malignancies.

Liu L et al.

Medcomm, 2025

41346570 (PubMed )
Supplement: MCO2-6-e70483-s002.xlsx › Tumour_cellularity

Clinicopathological and molecular characterization of KRAS wild-type pancreatic ductal adenocarcinomas reveals precursor lesions with oncogenic mutations and fusions in RAS pathway genes.

Toriyama K et al.

The Journal of Pathology, 2025

40317966 (PubMed )
Supplement: PATH-266-337-s002.zip › path6432-sup-0004-TableS4.xlsx › PDAC-057-ad

Beyond BRAFV600E: Investigating the Clinical and Genetic Spectrum of Langerhans Cell Histiocytosis in Children.

Tang X et al.

Cancer Medicine, 2024

Sclerosing melanocytic tumors with MAP2K1 in-frame deletions and copy number gains in 15q: A distinctive pathway of nevogenesis.

Hamad J et al.

Journal of Cutaneous Pathology, 2024

Clinicogenomic associations in childhood Langerhans cell histiocytosis: an international cohort study.

Kemps PG et al.

Blood Advances, 2023

36083130 (PubMed )
Supplement: BLOODA_ADV-2022-007947-mmc1.pdf

Clinical study of MAP2K1-mutated Langerhans cell histiocytosis in children.

Yang Y et al.

Journal of Cancer Research and Clinical Oncology, 2022

Genotype-Guided Medical Treatment of an Arteriovenous Malformation in a Child.

Lekwuttikarn R et al.

Jama Dermatology, 2019

Mutually exclusive recurrent somatic mutations in MAP2K1 and BRAF support a central role for ERK activation in LCH pathogenesis.

Chakraborty R et al.

Blood, 2014

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."