Varaico: Literature-Extracted Genetic Variants

Gene:MAP2K1
Variant:p.V60E
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MAP2K1

NM_002755.4:p.V60E

Associated Papers

Inflammatory Giant Cell Carcinoma of the Lung: Clinicopathologic, Immunohistochemical, and Next-generation Sequencing Study of 14 Cases.

Suster DI et al.

The American Journal of Surgical Pathology, 2024

Evolutionary history of MEK1 illuminates the nature of deleterious mutations.

Andrianova EP et al.

Proceedings of the National Academy of Sciences of the United States of America, 2023

37579140 (PubMed )
Supplement: pnas.2304184120.sapp.pdf

Molecular and clinicopathologic characterization of pediatric histiocytoses.

Hélias-Rodzewicz Z et al.

American Journal of Hematology, 2023

High-Throughput Functional Evaluation of MAP2K1 Variants in Cancer.

Mizuno S et al.

Molecular Cancer Therapeutics, 2023

Secondary Resistant Mutations to Small Molecule Inhibitors in Cancer Cells.

Hamid AB et al.

Cancers, 2020

32283832 (PubMed )
Supplement: cancers-12-00927-s001.pdf

The Immunogenic Potential of Recurrent Cancer Drug Resistance Mutations: An In Silico Study.

Punta M et al.

Frontiers in Immunology, 2020

33133066 (PubMed )
Supplement: Table_1.xlsx › Resistance-no-BCR-ABL1

Activated MEK cooperates with Cdkn2a and Pten loss to promote the development and maintenance of melanoma.

Yang H et al.

Oncogene, 2017

The genetic landscape of clinical resistance to RAF inhibition in metastatic melanoma.

Van Allen EM et al.

Cancer Discovery, 2014

A bipartite mechanism for ERK2 recognition by its cognate regulators and substrates.

Zhang J et al.

The Journal of Biological Chemistry, 2003

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."