Varaico: Literature-Extracted Genetic Variants

Gene:MAP2K1
Variant:p.S72G
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MAP2K1

NM_002755.4:p.S72G

Associated Papers

Evolutionary history of MEK1 illuminates the nature of deleterious mutations.

Andrianova EP et al.

Proceedings of the National Academy of Sciences of the United States of America, 2023

37579140 (PubMed )
Supplement: pnas.2304184120.sapp.pdf

High-Throughput Functional Evaluation of MAP2K1 Variants in Cancer.

Mizuno S et al.

Molecular Cancer Therapeutics, 2023

MEK inhibitor enhanced the antitumor effect of oxaliplatin and 5‑fluorouracil in MEK1 Q56P‑mutant colorectal cancer cells.

Jing C et al.

Molecular Medicine Reports, 2019

MEK inhibitor for gastric cancer with MEK1 gene mutations.

Sogabe S et al.

Molecular Cancer Therapeutics, 2014

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."