Varaico: Literature-Extracted Genetic Variants

Gene:MAP2K6
Variant:p.K82M
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MAP2K6

NM_002758.4:p.K82M

Associated Papers

A direct HDAC4-MAP kinase crosstalk activates muscle atrophy program.

Choi MC et al.

Molecular Cell, 2012

The Parkinson disease-associated protein kinase LRRK2 exhibits MAPKKK activity and phosphorylates MKK3/6 and MKK4/7, in vitro.

Gloeckner CJ et al.

Journal of Neurochemistry, 2009

TAO kinases mediate activation of p38 in response to DNA damage.

Raman M et al.

The Embo Journal, 2007

Crystal structure of the TAO2 kinase domain: activation and specificity of a Ste20p MAP3K.

Zhou T et al.

Structure (london, England : 1993), 2004

WNK1 activates ERK5 by an MEKK2/3-dependent mechanism.

Xu BE et al.

The Journal of Biological Chemistry, 2004

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."