Varaico: Literature-Extracted Genetic Variants

Gene:MAP3K1
Variant:p.A122V
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MAP3K1

NM_005921.2:p.A122V

Associated Papers

TP53 mutations identify high-risk events for peripheral T-cell lymphoma treated with CHOP-based chemotherapy.

Johnson WT et al.

Blood Advances, 2023

37078708 (PubMed )
Supplement: BLOODA_ADV-2023-009953-mmc1.xlsx › S1D_AITL_mutations

PIK3CA and MAP3K1 alterations imply luminal A status and are associated with clinical benefit from pan-PI3K inhibitor buparlisib and letrozole in ER+ metastatic breast cancer.

Nixon MJ et al.

Npj Breast Cancer, 2019

31552290 (PubMed )
Supplement: 41523_2019_126_MOESM1_ESM.xlsx › Supplementary_Dataset_1

MAP3K1 and MAP2K4 mutations are associated with sensitivity to MEK inhibitors in multiple cancer models.

Xue Z et al.

Cell Research, 2018

29795445 (PubMed )
Supplement: 41422_2018_44_MOESM7_ESM.xlsx › ___1
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."