Varaico: Literature-Extracted Genetic Variants

Gene:MAP3K21
Variant:p.N596I
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MAP3K21

NM_032435.3:p.N596I

Associated Papers

Recurrent MLK4 Loss-of-Function Mutations Suppress JNK Signaling to Promote Colon Tumorigenesis.

Marusiak AA et al.

Cancer Research, 2016

Mixed lineage kinase MLK4 is activated in colorectal cancers where it synergistically cooperates with activated RAS signaling in driving tumorigenesis.

Martini M et al.

Cancer Research, 2013

Absence of tyrosine kinase mutations in Japanese colorectal cancer patients.

Shao RX et al.

Oncogene, 2007

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."