Varaico: Literature-Extracted Genetic Variants

Gene:MAP3K3
Variant:p.K391M
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MAP3K3

NM_002401.5:p.K391M

Associated Papers

Phosphorylation of MEKK3 at threonine 294 promotes 14-3-3 association to inhibit nuclear factor kappaB activation.

Matitau AE et al.

The Journal of Biological Chemistry, 2008

Phosphorylation of serine 526 is required for MEKK3 activity, and association with 14-3-3 blocks dephosphorylation.

Fritz A et al.

The Journal of Biological Chemistry, 2006

WNK1 activates ERK5 by an MEKK2/3-dependent mechanism.

Xu BE et al.

The Journal of Biological Chemistry, 2004

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."