Varaico: Literature-Extracted Genetic Variants

Gene:MAPK1
Variant:p.T185A
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MAPK1

NM_002745.5:p.T185A

Associated Papers

ERK1/2 interaction with DHPS regulates eIF5A deoxyhypusination independently of ERK kinase activity.

Becker AE et al.

Cell Reports, 2024

39392755 (PubMed )
Supplement: NIHMS2031309-supplement-1.pdf

Targeting KRAS-mutant stomach/colorectal tumors by disrupting the ERK2-p53 complex.

Wang X et al.

Cell Reports, 2023

Droplet-based screening of phosphate transfer catalysis reveals how epistasis shapes MAP kinase interactions with substrates.

Scheele RA et al.

Nature Communications, 2022

KinaseMD: kinase mutations and drug response database.

Hu R et al.

Nucleic Acids Research, 2021

33137204 (PubMed )
Supplement: gkaa945_supplemental_files.zip › Supplementary_Table_S3.xlsx › Sheet1

ARL11 regulates lipopolysaccharide-stimulated macrophage activation by promoting mitogen-activated protein kinase (MAPK) signaling.

Arya SB et al.

The Journal of Biological Chemistry, 2018

29618517 (PubMed )
Supplement: supp_RA117.000727_133585_1_supp_100259_p5wtp8.pdf

Phenotypic Characterization of a Comprehensive Set of MAPK1/ERK2 Missense Mutants.

Brenan L et al.

Cell Reports, 2016

Nurr1 is phosphorylated by ERK2 in vitro and its phosphorylation upregulates tyrosine hydroxylase expression in SH-SY5Y cells.

Zhang T et al.

Neuroscience Letters, 2007

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."