Varaico: Literature-Extracted Genetic Variants

Gene:MAPK1
Variant:p.R172H
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MAPK1

NM_002745.5:p.R172H

Associated Papers

Loss of p53 and SMAD4 induces adenosquamous subtype pancreatic cancer in the absence of an oncogenic KRAS mutation.

Yang D et al.

Cell Reports. Medicine, 2024

Myc upregulates Ggct, γ-glutamylcyclotransferase to promote development of p53-deficient osteosarcoma.

Ueno T et al.

Cancer Science, 2024

RAS mutations in myeloid malignancies: revisiting old questions with novel insights and therapeutic perspectives.

Alawieh D et al.

Blood Cancer Journal, 2024

Genetic ablation of ketohexokinase C isoform impairs pancreatic cancer development.

Guccini I et al.

Iscience, 2023

Driver Mutations of Pancreatic Cancer Affect Ca2+ Signaling and ATP Production.

Stopa KB et al.

Function (oxford, England), 2023

Immunosuppression and outcomes in adult patients with de novo acute myeloid leukemia with normal karyotypes.

Ferraro F et al.

Proceedings of the National Academy of Sciences of the United States of America, 2021

34845035 (PubMed )
Supplement: pnas.2116427118.sd02.xlsx › mutations.2021.02.24

Transposon mutagenesis identifies cooperating genetic drivers during keratinocyte transformation and cutaneous squamous cell carcinoma progression.

Aiderus A et al.

Plos Genetics, 2021

Genomic characterization of Chinese ovarian clear cell carcinoma identifies driver genes by whole exome sequencing.

Yang Q et al.

Neoplasia (new York, N.y.), 2020

BRAFV600E drives dedifferentiation in small intestinal and colonic organoids and cooperates with mutant p53 and Apc loss in transformation.

Reischmann N et al.

Oncogene, 2020

Targeting the Oncogenic p53 Mutants in Colorectal Cancer and Other Solid Tumors.

Li H et al.

International Journal of Molecular Sciences, 2019

Analyzing tumor heterogeneity and driver genes in single myeloid leukemia cells with SBCapSeq.

Mann KM et al.

Nature Biotechnology, 2016

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."