Varaico: Literature-Extracted Genetic Variants

Gene:MAPK1
Variant:p.L156L
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MAPK1

NM_002745.5:p.L156L

Associated Papers

Inhibition of RAF Isoforms and Active Dimers by LY3009120 Leads to Anti-tumor Activities in RAS or BRAF Mutant Cancers.

Peng SB et al.

Cancer Cell, 2015

Non-hodgkin lymphoma in a patient with cardiofaciocutaneous syndrome.

Ohtake A et al.

Journal of Pediatric Hematology/oncology, 2011

BRAF V600E disrupts AZD6244-induced abrogation of negative feedback pathways between extracellular signal-regulated kinase and Raf proteins.

Friday BB et al.

Cancer Research, 2008

Different effects of point mutations within the B-Raf glycine-rich loop in colorectal tumors on mitogen-activated protein/extracellular signal-regulated kinase kinase/extracellular signal-regulated kinase and nuclear factor kappaB pathway and cellular transformation.

Ikenoue T et al.

Cancer Research, 2004

BRAF mutations in non-Hodgkin's lymphoma.

Lee JW et al.

British Journal of Cancer, 2003

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."