Associated Papers
A conserved arginine within the αC-helix of Erk1/2 is a latch of autoactivation and of oncogenic capabilities.
Soudah N et al.
The Journal of Biological Chemistry, 2023
Targeting lectin-like oxidized low-density lipoprotein receptor-1 triggers autophagic program in esophageal cancer.
Li C et al.
Cell Death and Differentiation, 2022
Monoubiquitination of p120-catenin is essential for TGFβ-induced epithelial-mesenchymal transition and tumor metastasis.
Wu Q et al.
Science Advances, 2020
Transcriptional regulation of autophagy-lysosomal function in BRAF-driven melanoma progression and chemoresistance.
Li S et al.
Nature Communications, 2019
STAT3 is a master regulator of epithelial identity and KRAS-driven tumorigenesis.
D'Amico S et al.
Genes & Development, 2018
30135074 (PubMed )
Supplement: supp_gad.311852.118_Supplemental_Figure4.pptx.pdf
Erk2 phosphorylation of Drp1 promotes mitochondrial fission and MAPK-driven tumor growth.
Kashatus JA et al.
Molecular Cell, 2015
Copper is required for oncogenic BRAF signalling and tumorigenesis.
Brady DC et al.
Nature, 2014
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