Varaico: Literature-Extracted Genetic Variants

Gene:MAPK1
Variant:p.Y64N
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MAPK1

NM_002745.5:p.Y64N

Associated Papers

ERK1/2 interaction with DHPS regulates eIF5A deoxyhypusination independently of ERK kinase activity.

Becker AE et al.

Cell Reports, 2024

39392755 (PubMed )
Supplement: NIHMS2031309-supplement-1.pdf

Critical APJ receptor residues in extracellular domains that influence effector selectivity.

Ashokan A et al.

The Febs Journal, 2021

TBK1 Suppresses RIPK1-Driven Apoptosis and Inflammation during Development and in Aging.

Xu D et al.

Cell, 2018

Rational design of non-resistant targeted cancer therapies.

Martínez-Jiménez F et al.

Scientific Reports, 2017

Variants of the yeast MAPK Mpk1 are fully functional independently of activation loop phosphorylation.

Goshen-Lago T et al.

Molecular Biology of the Cell, 2016

ERK mutations confer resistance to mitogen-activated protein kinase pathway inhibitors.

Goetz EM et al.

Cancer Research, 2014

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."