Varaico: Literature-Extracted Genetic Variants

Gene:MAPK3
Variant:p.Y204F
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MAPK3

NM_002746.3:p.Y204F

Associated Papers

A conserved arginine within the αC-helix of Erk1/2 is a latch of autoactivation and of oncogenic capabilities.

Soudah N et al.

The Journal of Biological Chemistry, 2023

Extracellular signal-regulated kinase (ERK) phosphorylates histone deacetylase 6 (HDAC6) at serine 1035 to stimulate cell migration.

Williams KA et al.

The Journal of Biological Chemistry, 2013

Somatically acquired JAK1 mutations in adult acute lymphoblastic leukemia.

Flex E et al.

The Journal of Experimental Medicine, 2008

Characterization of ERK1 activation site mutants and the effect on recognition by MEK1 and MEK2.

Butch ER et al.

The Journal of Biological Chemistry, 1996

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."