Varaico: Literature-Extracted Genetic Variants

Gene:MAPK6
Variant:p.S189A
Back to variants list

MAPK6

NM_002748.4:p.S189A

Associated Papers

ERK3/MAPK6 dictates CDC42/RAC1 activity and ARP2/3-dependent actin polymerization.

Bogucka-Janczi K et al.

Elife, 2023

Biochemical, cellular and structural characterization of novel and selective ERK3 inhibitors.

Grädler U et al.

Bioorganic & Medicinal Chemistry Letters, 2020

L290P/V mutations increase ERK3's cytoplasmic localization and migration/invasion-promoting capability in cancer cells.

Alsaran H et al.

Scientific Reports, 2017

C-terminal domain phosphorylation of ERK3 controlled by Cdk1 and Cdc14 regulates its stability in mitosis.

Tanguay PL et al.

The Biochemical Journal, 2010

Scaffolding by ERK3 regulates MK5 in development.

Schumacher S et al.

The Embo Journal, 2004

Nuclear export of ERK3 by a CRM1-dependent mechanism regulates its inhibitory action on cell cycle progression.

Julien C et al.

The Journal of Biological Chemistry, 2003

ERK3 is a constitutively nuclear protein kinase.

Cheng M et al.

The Journal of Biological Chemistry, 1996

Select a paper to view details
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."