Varaico: Literature-Extracted Genetic Variants

Gene:MAPT
Variant:p.A2T
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MAPT

NM_001377265.1:p.A2T

Associated Papers

An approach to predict and inhibit Amyloid Beta dimerization pattern in Alzheimer's disease.

Roy S et al.

Toxicology Reports, 2025

Impact of A2T and D23N Mutations on Tetrameric Aβ42 Barrel within a Dipalmitoylphosphatidylcholine Lipid Bilayer Membrane by Replica Exchange Molecular Dynamics.

Ngo ST et al.

The Journal of Physical Chemistry. B, 2020

Interplay of primary sequence, position and secondary RNA structure determines alternative splicing of LMNA in a pre-mature aging syndrome.

Shilo A et al.

Nucleic Acids Research, 2019

Alzheimer's amyloid-β A2T variant and its N-terminal peptides inhibit amyloid-β fibrillization and rescue the induced cytotoxicity.

Lin TW et al.

Plos One, 2017

Closing the tau loop: the missing tau mutation.

McCarthy A et al.

Brain : a Journal of Neurology, 2015

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."