Varaico: Literature-Extracted Genetic Variants

Gene:MAPT
Variant:p.A2V
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MAPT

NM_001377265.1:p.A2V

Associated Papers

An approach to predict and inhibit Amyloid Beta dimerization pattern in Alzheimer's disease.

Roy S et al.

Toxicology Reports, 2025

The AβA2V paradigm: From molecular insights to therapeutic strategies in Alzheimer's disease and primary tauopathies.

Diomede L et al.

Pharmacological Research, 2025

Mitochondrial CHCHD2: Disease-Associated Mutations, Physiological Functions, and Current Animal Models.

Kee TR et al.

Frontiers in Aging Neuroscience, 2021

Estrogens Inhibit Amyloid-β-Mediated Paired Helical Filament-Like Conformation of Tau Through Antioxidant Activity and miRNA 218 Regulation in hTau Mice.

Guglielmotto M et al.

Journal of Alzheimer's Disease : Jad, 2020

Identification of CHCHD2 mutations in patients with Alzheimer's disease, amyotrophic lateral sclerosis and frontotemporal dementia in China.

Liu X et al.

Molecular Medicine Reports, 2018

Mitochondrial CHCHD-Containing Proteins: Physiologic Functions and Link with Neurodegenerative Diseases.

Zhou ZD et al.

Molecular Neurobiology, 2017

The A2V mutation as a new tool for hindering Aβ aggregation: A neutron and x-ray diffraction study.

Cantu' L et al.

Scientific Reports, 2017

Alzheimer's Aβ peptides with disease-associated N-terminal modifications: influence of isomerisation, truncation and mutation on Cu2+ coordination.

Drew SC et al.

Plos One, 2010

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."