Varaico: Literature-Extracted Genetic Variants

Gene:MAPT
Variant:p.M31I
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MAPT

NM_001377265.1:p.M31I

Associated Papers

Efficient induction of motor neuron disease in transgenic G93A SOD1 mice by prion-like seeding.

Xu G et al.

Prion, 2026

Contribution of A-to-I RNA editing, M6A RNA Methylation, and Alternative Splicing to physiological brain aging and neurodegenerative diseases.

Tassinari V et al.

Mechanisms of Ageing and Development, 2023

cGAS and DDX41-STING mediated intrinsic immunity spreads intercellularly to promote neuroinflammation in SOD1 ALS model.

Tan HY et al.

Iscience, 2022

The Role of VCP Mutations in the Spectrum of Amyotrophic Lateral Sclerosis-Frontotemporal Dementia.

Scarian E et al.

Frontiers in Neurology, 2022

Variation in the vulnerability of mice expressing human superoxide dismutase 1 to prion-like seeding: a study of the influence of primary amino acid sequence.

Ayers JI et al.

Acta Neuropathologica Communications, 2021

Are Astrocytes the Predominant Cell Type for Activation of Nrf2 in Aging and Neurodegeneration?

Liddell JR

Antioxidants (basel, Switzerland), 2017

Distinct conformers of transmissible misfolded SOD1 distinguish human SOD1-FALS from other forms of familial and sporadic ALS.

Ayers JI et al.

Acta Neuropathologica, 2016

Prion-like propagation of mutant SOD1 misfolding and motor neuron disease spread along neuroanatomical pathways.

Ayers JI et al.

Acta Neuropathologica, 2016

Genetic rodent models of amyotrophic lateral sclerosis.

Van Den Bosch L

Journal of Biomedicine & Biotechnology, 2011

Genetics of amyotrophic lateral sclerosis.

Siddique T et al.

Human Molecular Genetics, 1996

Superoxide dismutase and neurofilament transgenic models of amyotrophic lateral sclerosis.

Morrison BM et al.

The Journal of Experimental Zoology, 0

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."