Varaico: Literature-Extracted Genetic Variants

Gene:MAPT
Variant:p.K311Q
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MAPT

NM_001377265.1:p.K311Q

Associated Papers

Acetylation Mimetic and Null Mutations Within the Filament Core of P301L Tau Have Varied Effects on Susceptibility to Seeding and Aggregation.

Smith ED et al.

Journal of Neurochemistry, 2025

Acetylation mimetic and null mutations within the filament core of P301L tau have varied effects on susceptibility to seeding and aggregation.

Smith ED et al.

Biorxiv : the Preprint Server for Biology, 2025

Impact of Lysine Acetylation Mutations on the Structure of Full-Length Tau Fibrils.

Dregni AJ et al.

Acs Chemical Neuroscience, 2025

Acetylation discriminates disease-specific tau deposition.

Chakraborty P et al.

Nature Communications, 2023

An HDAC6-dependent surveillance mechanism suppresses tau-mediated neurodegeneration and cognitive decline.

Trzeciakiewicz H et al.

Nature Communications, 2020

In Silico Evaluation of Acetylation Mimics in the 27 Lysine Residues of Human Tau Protein.

Kim YC et al.

Current Alzheimer Research, 2019

An acetylation-phosphorylation switch that regulates tau aggregation propensity and function.

Carlomagno Y et al.

The Journal of Biological Chemistry, 2017

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."