Associated Papers
Targeting 14-3-3θ-mediated TDP-43 pathology in amyotrophic lateral sclerosis and frontotemporal dementia mice.
Ke YD et al.
Neuron, 2024
Involvement of heterologous ubiquitination including linear ubiquitination in Alzheimer's disease and amyotrophic lateral sclerosis.
Sato Y et al.
Frontiers in Molecular Biosciences, 2023
Identification of TARDBP Gly298Ser as a founder mutation for amyotrophic lateral sclerosis in Southern China.
Xu F et al.
Bmc Medical Genomics, 2022
Molecular Mechanisms Underlying TDP-43 Pathology in Cellular and Animal Models of ALS and FTLD.
Wood A et al.
International Journal of Molecular Sciences, 2021
Amyotrophic Lateral Sclerosis Modifiers in Drosophila Reveal the Phospholipase D Pathway as a Potential Therapeutic Target.
Kankel MW et al.
Genetics, 2020
Characterizing TDP-43307-319 Oligomeric Assembly: Mechanistic and Structural Implications Involved in the Etiology of Amyotrophic Lateral Sclerosis.
Laos V et al.
Acs Chemical Neuroscience, 2019
The debated toxic role of aggregated TDP-43 in amyotrophic lateral sclerosis: a resolution in sight?
Hergesheimer RC et al.
Brain : a Journal of Neurology, 2019
TDP-43 enhances translation of specific mRNAs linked to neurodegenerative disease.
Neelagandan N et al.
Nucleic Acids Research, 2019
Therapeutic and diagnostic challenges for frontotemporal dementia.
D'Alton S et al.
Frontiers in Aging Neuroscience, 2014
Similar dose-dependence of motor neuron cell death caused by wild type human TDP-43 and mutants with ALS-associated amino acid substitutions.
Wu LS et al.
Journal of Biomedical Science, 2013
Accelerated disease onset with stabilized familial amyotrophic lateral sclerosis (ALS)-linked mutant TDP-43 proteins.
Watanabe S et al.
The Journal of Biological Chemistry, 2013
Drosophila Answers to TDP-43 Proteinopathies.
Romano M et al.
Journal of Amino Acids, 2012
Understanding the role of TDP-43 and FUS/TLS in ALS and beyond.
Da Cruz S et al.
Current Opinion in Neurobiology, 2011
Progranulin and TDP-43: mechanistic links and future directions.
Kumar-Singh S
Journal of Molecular Neuroscience : Mn, 2011
Cytoplasmic mislocalization of TDP-43 is toxic to neurons and enhanced by a mutation associated with familial amyotrophic lateral sclerosis.
Barmada SJ et al.
The Journal of Neuroscience : the Official Journal of the Society for Neuroscience, 2010
Pathogenic TARDBP mutations in amyotrophic lateral sclerosis and frontotemporal dementia: disease-associated pathways.
Barmada SJ et al.
Reviews in the Neurosciences, 2010
[Frontotemporal dementia (FTD) and genetic mutations including progranulin gene].
Arai T et al.
Rinsho Shinkeigaku = Clinical Neurology, 2008