Varaico: Literature-Extracted Genetic Variants

Gene:MARK2
Variant:p.K82R
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MARK2

NM_001039469.3:p.K82R

Associated Papers

The KLDpT activation loop motif is critical for MARK kinase activity.

Sonntag T et al.

Plos One, 2019

Interconversion of inactive to active conformation of MARK2: Insights from molecular modeling and molecular dynamics simulation.

Ahrari S et al.

Archives of Biochemistry and Biophysics, 2017

Structural basis for the regulation of maternal embryonic leucine zipper kinase.

Cao LS et al.

Plos One, 2013

DAPK activates MARK1/2 to regulate microtubule assembly, neuronal differentiation, and tau toxicity.

Wu PR et al.

Cell Death and Differentiation, 2011

Structure and function of polarity-inducing kinase family MARK/Par-1 within the branch of AMPK/Snf1-related kinases.

Marx A et al.

Faseb Journal : Official Publication of the Federation of American Societies for Experimental Biology, 2010

Structure of the catalytic and ubiquitin-associated domains of the protein kinase MARK/Par-1.

Panneerselvam S et al.

Structure (london, England : 1993), 2006

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."