Associated Papers
Matrin-3 forms spherical and wormlike assemblies that are modulated by RNA binding and ALS/FTD-associated mutations.
Sprunger ML et al.
Molecular Cell, 2025
Genetic architecture of amyotrophic lateral sclerosis: a comprehensive review.
Yuan L et al.
Journal of Genetics and Genomics = Yi Chuan Xue Bao, 2025
A systematic review and functional in-silico analysis of genes and variants associated with amyotrophic lateral sclerosis.
Arreola-Aldape CA et al.
Frontiers in Neuroscience, 2025
The role of Matrin-3 in physiology and its dysregulation in disease.
Sprunger ML et al.
Biochemical Society Transactions, 2024
MATR3's Role beyond the Nuclear Matrix: From Gene Regulation to Its Implications in Amyotrophic Lateral Sclerosis and Other Diseases.
Santos JR et al.
Cells, 2024
MATR3-antisense LINE1 RNA meshwork scaffolds higher-order chromatin organization.
Zhang Y et al.
Embo Reports, 2023
Studies of Genetic and Proteomic Risk Factors of Amyotrophic Lateral Sclerosis Inspire Biomarker Development and Gene Therapy.
Bagyinszky E et al.
Cells, 2023
MATR3 P154S knock-in mice do not exhibit motor, muscle or neuropathologic features of ALS.
Dominick M et al.
Biochemical and Biophysical Research Communications, 2023
1H, 13C and 15N resonance assignments and solution structures of the two RRM domains of Matrin-3.
He F et al.
Biomolecular Nmr Assignments, 2022
Molecular determinants and modifiers of Matrin-3 toxicity, condensate dynamics, and droplet morphology.
Sprunger ML et al.
Iscience, 2022
MATR3 haploinsufficiency and early-onset neurodegeneration.
Zech M et al.
Brain : a Journal of Neurology, 2021
Destination Amyotrophic Lateral Sclerosis.
Keon M et al.
Frontiers in Neurology, 2021
Knockdown of genes involved in axonal transport enhances the toxicity of human neuromuscular disease-linked MATR3 mutations in Drosophila.
Zhao M et al.
Febs Letters, 2020
Case Report: Early-Onset Behavioral Variant Frontotemporal Dementia in Patient With Retrotransposed Full-Length Transcript of Matrin-3 Variant 5.
Castro M et al.
Frontiers in Neurology, 2020
Identification and characterization of novel and rare susceptible variants in Indian amyotrophic lateral sclerosis patients.
Narain P et al.
Neurogenetics, 2019
Systematic analysis of the intersection of disease mutations with protein modifications.
Simpson CM et al.
Bmc Medical Genomics, 2019
N-terminal sequences in matrin 3 mediate phase separation into droplet-like structures that recruit TDP43 variants lacking RNA binding elements.
Gallego-Iradi MC et al.
Laboratory Investigation; a Journal of Technical Methods and Pathology, 2019
Analysis of spinal and muscle pathology in transgenic mice overexpressing wild-type and ALS-linked mutant MATR3.
Moloney C et al.
Acta Neuropathologica Communications, 2018
Matrin 3-dependent neurotoxicity is modified by nucleic acid binding and nucleocytoplasmic localization.
Malik AM et al.
Elife, 2018
Characterization of gene regulation and protein interaction networks for Matrin 3 encoding mutations linked to amyotrophic lateral sclerosis and myopathy.
Iradi MCG et al.
Scientific Reports, 2018
Novel genes associated with amyotrophic lateral sclerosis: diagnostic and clinical implications.
Chia R et al.
The Lancet. Neurology, 2018
ALS Associated Mutations in Matrin 3 Alter Protein-Protein Interactions and Impede mRNA Nuclear Export.
Boehringer A et al.
Scientific Reports, 2017
Matrin 3 variants are frequent in Italian ALS patients.
Marangi G et al.
Neurobiology of Aging, 2017
Heterogeneity of Matrin 3 in the developing and aging murine central nervous system.
Rayaprolu S et al.
The Journal of Comparative Neurology, 2016
Amyotrophic lateral sclerosis: recent genetic highlights.
White MA et al.
Current Opinion in Neurology, 2016
New ALS-Related Genes Expand the Spectrum Paradigm of Amyotrophic Lateral Sclerosis.
Sabatelli M et al.
Brain Pathology (zurich, Switzerland), 2016
Genetic architecture of ALS in Sardinia.
Borghero G et al.
Neurobiology of Aging, 2014
Mutations in the Matrin 3 gene cause familial amyotrophic lateral sclerosis.
Johnson JO et al.
Nature Neuroscience, 2014
[Clinical statistics of myasthenia gravis, progressive muscular dystrophy and amyotrophic lateral sclerosis].
Unoya K
[kango Gijutsu] : [nursing Technique], 1973
Unraveling the multifaceted insights into amyotrophic lateral sclerosis: Genetic underpinnings, pathogenesis, and therapeutic horizons.
Sharma R et al.
Mutation Research. Reviews in Mutation Research, 0