Associated Papers
Directed evolution of metalloproteinase inhibitor TIMP-1 for selective inhibition of MMP-9 exploits catalytic and fibronectin domain interactions.
Shoari A et al.
The Journal of Biological Chemistry, 2025
The reovirus variant RP116 is oncolytic in immunocompetent models and generates reduced neutralizing antibodies to Type 3 Dearing.
Song KH et al.
Molecular Therapy. Oncology, 2024
39354956 (PubMed )
Supplement: mmc2.pdf
AKT activation because of PTEN loss upregulates xCT via GSK3β/NRF2, leading to inhibition of ferroptosis in PTEN-mutant tumor cells.
Cahuzac KM et al.
Cell Reports, 2023
37210723 (PubMed )
Supplement: NIHMS1908585-supplement-supplementary_material.pdf
Synthetic Cannabinoids Induce Autophagy and Mitochondrial Apoptotic Pathways in Human Glioblastoma Cells Independently of Deficiency in TP53 or PTEN Tumor Suppressors.
Ellert-Miklaszewska A et al.
Cancers, 2021
Cdk4 and Cdk6 Couple the Cell-Cycle Machinery to Cell Growth via mTORC1.
Romero-Pozuelo J et al.
Cell Reports, 2020
DEPTOR at the Nexus of Cancer, Metabolism, and Immunity.
Caron A et al.
Physiological Reviews, 2018
Micronuclei Frequency in Tumors Is a Predictive Biomarker for Genetic Instability and Sensitivity to the DNA Repair Inhibitor AsiDNA.
Jdey W et al.
Cancer Research, 2017
mTORC2 Regulates Amino Acid Metabolism in Cancer by Phosphorylation of the Cystine-Glutamate Antiporter xCT.
Gu Y et al.
Molecular Cell, 2017
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