Associated Papers
Human melanocortin 1 receptor-mediated ubiquitination of nonvisual arrestins. Role of Mahogunin Ring Finger 1 E3 ligase.
Abrisqueta M et al.
Biochimica Et Biophysica Acta. Molecular Cell Research, 2018
MC1R, the cAMP pathway, and the response to solar UV: extending the horizon beyond pigmentation.
García-Borrón JC et al.
Pigment Cell & Melanoma Research, 2014
Melanoma risk associated with MC1R gene variants in Latvia and the functional analysis of rare variants.
Ozola A et al.
Cancer Genetics, 2013
Functional status and relationships of melanocortin 1 receptor signaling to the cAMP and extracellular signal-regulated protein kinases 1 and 2 pathways in human melanoma cells.
Herraiz C et al.
The International Journal of Biochemistry & Cell Biology, 2012
N-glycosylation of the human melanocortin 1 receptor: occupancy of glycosylation sequons and functional role.
Herraiz C et al.
Pigment Cell & Melanoma Research, 2011
Melanocortin 1 receptor mutations impact differentially on signalling to the cAMP and the ERK mitogen-activated protein kinase pathways.
Herraiz C et al.
Febs Letters, 2009
Identification and functional analysis of novel variants of the human melanocortin 1 receptor found in melanoma patients.
Pérez Oliva AB et al.
Human Mutation, 2009
Comprehensive evaluation of allele frequency differences of MC1R variants across populations.
Gerstenblith MR et al.
Human Mutation, 2007
Melanocortin-1 receptor: loss of function mutations and skin cancer.
Mumm CD et al.
Dermatology Online Journal, 2006
Inactivating mutations of G protein-coupled receptors and diseases: structure-function insights and therapeutic implications.
Tao YX
Pharmacology & Therapeutics, 2006
Variant amino acids in different domains of the human melanocortin 1 receptor impair cell surface expression.
Sánchez-Laorden BL et al.
Cellular and Molecular Biology (noisy-le-grand, France), 2006
Effect of MELANOTAN, [Nle(4), D-Phe(7)]-alpha-MSH, on melanin synthesis in humans with MC1R variant alleles.
Fitzgerald LM et al.
Peptides, 2006
Dimerization of the human melanocortin 1 receptor: functional consequences and dominant-negative effects.
Sánchez-Laorden BL et al.
The Journal of Investigative Dermatology, 2006
Melanocortin-1 receptor structure and functional regulation.
García-Borrón JC et al.
Pigment Cell Research, 2005
The relation between melanocortin 1 receptor (MC1R) variation and the generation of phenotypic diversity in the cutaneous response to ultraviolet radiation.
Wong TH et al.
Peptides, 2005
Pharmacological characterization of loss of function mutations of the human melanocortin 1 receptor that are associated with red hair.
Ringholm A et al.
The Journal of Investigative Dermatology, 2004
Agonist-independent, high constitutive activity of the human melanocortin 1 receptor.
Sánchez-Más J et al.
Pigment Cell Research, 2004
Loss-of-function variants of the human melanocortin-1 receptor gene in melanoma cells define structural determinants of receptor function.
Sánchez Más J et al.
European Journal of Biochemistry, 2002