Associated Papers
Large scale clinical exome sequencing uncovers the scope and severity of skin disorders associated with MC1R genetic variants.
Moore BS et al.
Genetics in Medicine : Official Journal of the American College of Medical Genetics, 2021
Molecular characterization of coat color gene in Sahiwal versus Karan Fries bovine.
Goud TS et al.
Journal, Genetic Engineering & Biotechnology, 2021
Pharmacological characterization of three chicken melanocortin-3 receptor mutants.
Zhang HJ et al.
Domestic Animal Endocrinology, 2021
Identification and sequence characterization of melanocortin 1 receptor gene (MC1R) in Bos indicus versus (Bos taurus X Bos indicus).
Goud TS et al.
Animal Biotechnology, 2020
Mc1r gene in Astroblepus pholeter and Astyanax mexicanus: Convergent regressive evolution of pigmentation across cavefish species.
Espinasa L et al.
Developmental Biology, 2018
The Contribution of Neanderthals to Phenotypic Variation in Modern Humans.
Dannemann M et al.
American Journal of Human Genetics, 2017
A large French case-control study emphasizes the role of rare Mc1R variants in melanoma risk.
Hu HH et al.
Biomed Research International, 2014
Functional status and relationships of melanocortin 1 receptor signaling to the cAMP and extracellular signal-regulated protein kinases 1 and 2 pathways in human melanoma cells.
Herraiz C et al.
The International Journal of Biochemistry & Cell Biology, 2012
MC1R genotypes and risk of melanoma before age 40 years: a population-based case-control-family study.
Cust AE et al.
International Journal of Cancer, 2012
Nucleotide diversity of the melanocortin 1 receptor gene (MC1R) in the gayal (Bos frontalis).
Xi D et al.
Molecular Biology Reports, 2012
The E92K melanocortin 1 receptor mutant induces cAMP production and arrestin recruitment but not ERK activity indicating biased constitutive signaling.
Benned-Jensen T et al.
Plos One, 2011
The role of MC1R gene in buffalo coat color.
Miao Y et al.
Science China. Life Sciences, 2010
Role of key-regulator genes in melanoma susceptibility and pathogenesis among patients from South Italy.
Casula M et al.
Bmc Cancer, 2009
Comprehensive evaluation of allele frequency differences of MC1R variants across populations.
Gerstenblith MR et al.
Human Mutation, 2007
Population-based study of natural variation in the melanocortin-1 receptor gene and melanoma.
Kanetsky PA et al.
Cancer Research, 2006
Re: Association between endothelin receptor B nonsynonymous variants and melanoma risk.
Thirumaran RK et al.
Journal of the National Cancer Institute, 2006
Inactivating mutations of G protein-coupled receptors and diseases: structure-function insights and therapeutic implications.
Tao YX
Pharmacology & Therapeutics, 2006
MC1R germline variants confer risk for BRAF-mutant melanoma.
Landi MT et al.
Science (new York, N.y.), 2006
Contribution of melanocortin-1 receptor gene variants to sporadic cutaneous melanoma risk in a population in central Italy: a case-control study.
Fargnoli MC et al.
Melanoma Research, 2006
The relation between melanocortin 1 receptor (MC1R) variation and the generation of phenotypic diversity in the cutaneous response to ultraviolet radiation.
Wong TH et al.
Peptides, 2005
MC1R, ASIP, and DNA repair in sporadic and familial melanoma in a Mediterranean population.
Landi MT et al.
Journal of the National Cancer Institute, 2005
Characterization of melanocortin-1 receptor gene variants in uveal melanoma patients.
Metzelaar-Blok JA et al.
Investigative Ophthalmology & Visual Science, 2001
Melanocortin 1 receptor (MC1R) gene variants are associated with an increased risk for cutaneous melanoma which is largely independent of skin type and hair color.
Kennedy C et al.
The Journal of Investigative Dermatology, 2001
Melanocortin-1 receptor gene variants determine the risk of nonmelanoma skin cancer independently of fair skin and red hair.
Bastiaens MT et al.
American Journal of Human Genetics, 2001