Associated Papers
Dissecting the Impact of α-MSH-MC1R-cAMP Signaling on UVA-Induced Stress in Fibroblasts - Implications for Regulation of Cutaneous Photoaging.
Böhm M et al.
Aging and Disease, 2026
Rare Germline Variants in CDKN2A-Negative Children and Adolescents With Cutaneous Melanoma.
Johansson PA et al.
Pigment Cell & Melanoma Research, 2026
Germline MC1R Variant Status and Efficacy of Immune Checkpoint Inhibitors in Patients With Advanced Melanoma.
Yang M et al.
Pigment Cell & Melanoma Research, 2025
Assessing MC1R Variants in Lentigo Maligna Melanoma within the Utah Population.
Jiang A et al.
Cancer Research Communications, 2025
Investigation of the MC1R Gene Sequence Variation Using Oxford Nanopore Sequencing.
Branicki W et al.
Electrophoresis, 2025
An overview of benefits and risks of chronic melanocortin-1 receptor activation.
Böhm M et al.
Journal of the European Academy of Dermatology and Venereology : Jeadv, 2025
Melanoma-associated melanocortin 1 receptor variants confer redox signaling-dependent protection against oxidative DNA damage.
Castejón-Griñán M et al.
Redox Biology, 2024
Familial Melanoma Phenotype With Xeroderma Pigmentosum Group C (XP-C) Genotype - The Putative Role of MC1R Polymorphism as Modifier.
Leidenz FAB et al.
Dermatology Practical & Conceptual, 2024
Unveiling the genetic landscape of hereditary melanoma: From susceptibility to surveillance.
Zheng C et al.
Cancer Treatment and Research Communications, 2024
High- and intermediate-risk susceptibility variants in melanoma families from the Mediterranean area: A multicentre cohort from the MelaNostrum Consortium.
Pellegrini C et al.
Journal of the European Academy of Dermatology and Venereology : Jeadv, 2023
Characterization of Potential Melanoma Predisposition Genes in High-Risk Brazilian Patients.
Soares de Sá BC et al.
International Journal of Molecular Sciences, 2023
UV-radiation and MC1R germline mutations are risk factors for the development of conventional and spitzoid melanomas in children and adolescents.
Liebmann A et al.
Ebiomedicine, 2023
MC1R signaling through the cAMP-CREB/ATF-1 and ERK-NFκB pathways accelerates G1/S transition promoting breast cancer progression.
Chelakkot VS et al.
Npj Precision Oncology, 2023
The MC1R r allele does not increase melanoma risk in MITF E318K carriers.
Wallingford CK et al.
The British Journal of Dermatology, 2023
Melanocortin 1 receptor variants and their association with phenotypic characteristics and sporadic multiple primary melanomas in a cohort of 402 Spanish subjects.
Vírseda-González D et al.
Experimental Dermatology, 2023
Additional predictions for forensic DNA phenotyping of externally visible characteristics using the ForenSeq and Imagen kits.
Elkins KM et al.
Journal of Forensic Sciences, 2023
Destabilization of mutated human PUS3 protein causes intellectual disability.
Lin TY et al.
Human Mutation, 2022
Aberrant expression of agouti signaling protein (ASIP) as a cause of monogenic severe childhood obesity.
Kempf E et al.
Nature Metabolism, 2022
Melanoma in children and adolescents: analysis of susceptibility genes in 123 Italian patients.
Pellegrini C et al.
Journal of the European Academy of Dermatology and Venereology : Jeadv, 2022
Genetic diversity of the melanocortin-1 receptor in an admixed population of Rio de Janeiro: Structural and functional impacts of Cys35Tyr variant.
Neitzke-Montinelli V et al.
Plos One, 2022
Large scale clinical exome sequencing uncovers the scope and severity of skin disorders associated with MC1R genetic variants.
Moore BS et al.
Genetics in Medicine : Official Journal of the American College of Medical Genetics, 2021
Genetic Variants and Somatic Alterations Associated with MITF-E318K Germline Mutation in Melanoma Patients.
Vergani E et al.
Genes, 2021
Familial Melanoma and Susceptibility Genes: A Review of the Most Common Clinical and Dermoscopic Phenotypic Aspect, Associated Malignancies and Practical Tips for Management.
Zocchi L et al.
Journal of Clinical Medicine, 2021
The α-melanocyte-stimulating hormone/melanocortin-1 receptor interaction: A driver of pleiotropic effects beyond pigmentation.
Herraiz C et al.
Pigment Cell & Melanoma Research, 2021
A Randomized Trial of Precision Prevention Materials to Improve Primary and Secondary Melanoma Prevention Activities among Individuals with Limited Melanoma Risk Phenotypes.
Lacson JCA et al.
Cancers, 2021
Influence of germline genetic variants on dermoscopic features of melanoma.
Pozzobon FC et al.
Pigment Cell & Melanoma Research, 2021
Skin pigmentation and its control: From ultraviolet radiation to stem cells.
Yardman-Frank JM et al.
Experimental Dermatology, 2021
The role of MC1R gene variants and phenotypical features in predicting high nevus count.
van der Poel LAJ et al.
Melanoma Research, 2020
MC1R variants and cutaneous melanoma risk according to histological type, body site, and Breslow thickness: a pooled analysis from the M-SKIP project.
Caini S et al.
Melanoma Research, 2020
Melanocortin-1 receptor (MC1R) genotypes do not correlate with size in two cohorts of medium-to-giant congenital melanocytic nevi.
Calbet-Llopart N et al.
Pigment Cell & Melanoma Research, 2020
Melanoma Risk and Melanocyte Biology.
Bertrand JU et al.
Acta Dermato-venereologica, 2020
MC1R variants and associations with pigmentation characteristics and genetic ancestry in a Hispanic, predominately Puerto Rican, population.
Smit AK et al.
Scientific Reports, 2020
Inherited MC1R variants in patients with melanoma are associated with better survival in women.
Lira FE et al.
The British Journal of Dermatology, 2020
The GenomeAsia 100K Project enables genetic discoveries across Asia.
Unknown Author
Nature, 2019
High naevus count and MC1R red hair alleles contribute synergistically to increased melanoma risk.
Duffy DL et al.
The British Journal of Dermatology, 2019
MC1R Variation in a New Mexico Population.
White KAM et al.
Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology, 2019
The complementary effect of rs1042522 in TP53 and rs1805007 in MC1R is associated with an elevated risk of cutaneous melanoma in Latvian population.
Ozola A et al.
Oncology Letters, 2019
The Melanocortin 1 receptor and its influence on naevi and melanoma in dark-skinned phenotypes.
Smith DJM
The Australasian Journal of Dermatology, 2019
A study in scarlet: MC1R as the main predictor of red hair and exemplar of the flip-flop effect.
Zorina-Lichtenwalter K et al.
Human Molecular Genetics, 2019
Phenotypic and genotypic analysis of amelanotic and hypomelanotic melanoma patients.
Rayner JE et al.
Journal of the European Academy of Dermatology and Venereology : Jeadv, 2019
Multigene panel sequencing of established and candidate melanoma susceptibility genes in a large cohort of Dutch non-CDKN2A/CDK4 melanoma families.
Potjer TP et al.
International Journal of Cancer, 2019
MC1R variants in childhood and adolescent melanoma: a retrospective pooled analysis of a multicentre cohort.
Pellegrini C et al.
The Lancet. Child & Adolescent Health, 2019