Associated Papers
Genetic architecture of multiple primary cutaneous melanoma in the absence of high-penetrance susceptibility genes.
Johansson PA et al.
The Journal of Investigative Dermatology, 2026
Dissecting the Impact of α-MSH-MC1R-cAMP Signaling on UVA-Induced Stress in Fibroblasts - Implications for Regulation of Cutaneous Photoaging.
Böhm M et al.
Aging and Disease, 2026
Rare Germline Variants in CDKN2A-Negative Children and Adolescents With Cutaneous Melanoma.
Johansson PA et al.
Pigment Cell & Melanoma Research, 2026
Cutaneous Melanoma Risk Assessment among Individuals with a High-Risk Nevus Phenotype.
Polo-Silveira L et al.
The Journal of Investigative Dermatology, 2025
Polymorphism of Melanocortin Receptor Genes-Association with Inflammatory Traits and Diseases.
Bardhan M et al.
Diseases (basel, Switzerland), 2025
UVA-induced DNA damage and mutations in human melanocytes: relevance for melanoma mutations.
Jin SG et al.
Nucleic Acids Research, 2025
Genetics of Skin, Hair, and Eye Color in Human Pigmentation Disorders.
Manga P et al.
Annals of Human Genetics, 2025
Germline MC1R Variant Status and Efficacy of Immune Checkpoint Inhibitors in Patients With Advanced Melanoma.
Yang M et al.
Pigment Cell & Melanoma Research, 2025
Assessing MC1R Variants in Lentigo Maligna Melanoma within the Utah Population.
Jiang A et al.
Cancer Research Communications, 2025
Germline Non-CDKN2A Variants in Melanoma and Associated Hereditary Cancer Syndromes.
Fiasconaro CA et al.
Diseases (basel, Switzerland), 2025
Investigation of the MC1R Gene Sequence Variation Using Oxford Nanopore Sequencing.
Branicki W et al.
Electrophoresis, 2025
Polygenic Risk Score Analysis of 37 SNPs Associated with Melanoma Risk in Colombian Population.
Tovar-Parra D et al.
International Journal of Molecular Sciences, 2025
An overview of benefits and risks of chronic melanocortin-1 receptor activation.
Böhm M et al.
Journal of the European Academy of Dermatology and Venereology : Jeadv, 2025
Germline loss-of-function variant in the E3 ubiquitin ligase TRAF2 in a young adult patient with medulloblastoma: a case report.
Vo JN et al.
Acta Neuropathologica Communications, 2024
Melanocortin 1 receptor mediates melanin production by interacting with the BBSome in primary cilia.
Tian X et al.
Plos Biology, 2024
Molecular Basis of MC1R Activation: Mutation-Induced Alterations in Structural Dynamics.
Cavatão FG et al.
Proteins, 2024
Journey through the spectacular landscape of melanocortin 1 receptor.
Upadhyay PR et al.
Pigment Cell & Melanoma Research, 2024
Skin colour: A window into human phenotypic evolution and environmental adaptation.
Liu J et al.
Molecular Ecology, 2024
The impact of genetic variants related to vitamin D and autoimmunity: A systematic review.
Trefilio LM et al.
Heliyon, 2024
MITF E318K: A rare homozygous case with multiple primary melanoma.
Wallingford CK et al.
Pigment Cell & Melanoma Research, 2024
Unveiling the genetic landscape of hereditary melanoma: From susceptibility to surveillance.
Zheng C et al.
Cancer Treatment and Research Communications, 2024
High- and intermediate-risk susceptibility variants in melanoma families from the Mediterranean area: A multicentre cohort from the MelaNostrum Consortium.
Pellegrini C et al.
Journal of the European Academy of Dermatology and Venereology : Jeadv, 2023
Characterization of Potential Melanoma Predisposition Genes in High-Risk Brazilian Patients.
Soares de Sá BC et al.
International Journal of Molecular Sciences, 2023
TINF2 is a major susceptibility gene in Danish patients with multiple primary melanoma.
Jensen MR et al.
Hgg Advances, 2023
UV-radiation and MC1R germline mutations are risk factors for the development of conventional and spitzoid melanomas in children and adolescents.
Liebmann A et al.
Ebiomedicine, 2023
A Side-by-Side Comparison of Wildtype and Variant Melanocortin 1 Receptor Signaling with Emphasis on Protection against Oxidative Damage to DNA.
Cerdido S et al.
International Journal of Molecular Sciences, 2023
MC1R signaling through the cAMP-CREB/ATF-1 and ERK-NFκB pathways accelerates G1/S transition promoting breast cancer progression.
Chelakkot VS et al.
Npj Precision Oncology, 2023
Forensic DNA Phenotyping: Genes and Genetic Variants for Eye Color Prediction.
Brancato D et al.
Genes, 2023
The Role of Gender Pharmacogenetics in the Personalization of Drug Treatment.
Cecchin E et al.
The Journal of Pharmacology and Experimental Therapeutics, 2023
Phenotypic and Dermoscopic Patterns of Familial Melanocytic Lesions: A Pilot Study in a Third-Level Center.
Roccuzzo G et al.
Cancers, 2023
The MC1R r allele does not increase melanoma risk in MITF E318K carriers.
Wallingford CK et al.
The British Journal of Dermatology, 2023
Melanocortin 1 receptor variants and their association with phenotypic characteristics and sporadic multiple primary melanomas in a cohort of 402 Spanish subjects.
Vírseda-González D et al.
Experimental Dermatology, 2023
AMPK Phosphorylates ZDHHC13 to Increase MC1R Activity and Suppress Melanomagenesis.
Sun Y et al.
Cancer Research, 2023
Mechanisms and implications in gene polymorphism mediated diverse reponses to sedatives, analgesics and muscle relaxants.
Sun Y et al.
Korean Journal of Anesthesiology, 2023
Cutaneous Melanoma and Glioblastoma Multiforme Association-Case Presentation and Literature Review.
Orzan OA et al.
Diagnostics (basel, Switzerland), 2023
Genome-wide data from medieval German Jews show that the Ashkenazi founder event pre-dated the 14th century.
Waldman S et al.
Cell, 2022
Aberrant expression of agouti signaling protein (ASIP) as a cause of monogenic severe childhood obesity.
Kempf E et al.
Nature Metabolism, 2022
Genome-wide association study of pain sensitivity assessed by questionnaire and the cold pressor test.
Fontanillas P et al.
Pain, 2022
Defining novel causal SNPs and linked phenotypes at melanoma-associated loci.
Castaneda-Garcia C et al.
Human Molecular Genetics, 2022
PRECOGx: exploring GPCR signaling mechanisms with deep protein representations.
Matic M et al.
Nucleic Acids Research, 2022
MC1R Functions, Expression, and Implications for Targeted Therapy.
Guida S et al.
The Journal of Investigative Dermatology, 2022