Varaico: Literature-Extracted Genetic Variants

Gene:MC3R
Variant:p.R151C
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MC3R

NM_019888.3:p.R151C

Associated Papers

An overview of benefits and risks of chronic melanocortin-1 receptor activation.

Böhm M et al.

Journal of the European Academy of Dermatology and Venereology : Jeadv, 2025

Biased signaling in naturally occurring mutations of G protein-coupled receptors associated with diverse human diseases.

Yang LK et al.

Biochimica Et Biophysica Acta. Molecular Basis of Disease, 2021

MC1R is dispensable for the proteinuria reducing and glomerular protective effect of melanocortin therapy.

Qiao Y et al.

Scientific Reports, 2016

Melanocortin-1 receptor structure and functional regulation.

García-Borrón JC et al.

Pigment Cell Research, 2005

Alpha-melanocyte-stimulating hormone suppresses antigen-induced lymphocyte proliferation in humans independently of melanocortin 1 receptor gene status.

Cooper A et al.

Journal of Immunology (baltimore, Md. : 1950), 2005

Gene polymorphisms and their effects in the melanocortin system.

Carroll L et al.

Peptides, 2005

Assessment of polymorphic variants in the melanocortin-1 receptor gene with cutaneous pigmentation using an evolutionary approach.

Kanetsky PA et al.

Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology, 2004

Four novel variants in MC1R in red-haired South African individuals of European descent: S83P, Y152X, A171D, P256S.

John PR et al.

Human Mutation, 2002

Characterization of melanocyte stimulating hormone receptor variant alleles in twins with red hair.

Box NF et al.

Human Molecular Genetics, 1997

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."