Varaico: Literature-Extracted Genetic Variants

Gene:MC3R
Variant:p.G240W
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MC3R

NM_019888.3:p.G240W

Associated Papers

Cross-species studies implicate the melanocortin 3 receptor more strongly in the control of pubertal development than energy balance.

Duckett K et al.

Molecular Metabolism, 2026

Effect of a partial loss of function MC3R mutation on MC3R+GHSR-1A heterodimer activity and RNF11 regulation.

Durhan ST et al.

Journal of Endocrinological Investigation, 2025

Pro-Opiomelanocortin and Melanocortin Receptor 3 and 4 Mutations in Genetic Obesity.

Yanik T et al.

Biomolecules, 2025

Medical semiology of patients with monogenic obesity: A systematic review.

Renard E et al.

Obesity Reviews : an Official Journal of the International Association for the Study of Obesity, 2024

MC3R links nutritional state to childhood growth and the timing of puberty.

Lam BYH et al.

Nature, 2021

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."