Varaico: Literature-Extracted Genetic Variants

Gene:MC4R
Variant:p.T312A
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MC4R

NM_005912.3:p.T312A

Associated Papers

Constitutive cholesterol-dependent endocytosis of melanocortin-4 receptor (MC4R) is essential to maintain receptor responsiveness to α-melanocyte-stimulating hormone (α-MSH).

McDaniel FK et al.

The Journal of Biological Chemistry, 2012

Molecular mechanism of the intracellular segments of the melanocortin-4 receptor for NDP-MSH signaling.

Yang Y et al.

Biochemistry, 2005

Regulation of melanocortin-4 receptor signaling: agonist-mediated desensitization and internalization.

Shinyama H et al.

Endocrinology, 2003

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."