Associated Papers
High-resolution deep mutational scanning of the melanocortin-4 receptor enables target characterization for drug discovery.
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Elife, 2025
40202051 (PubMed )
Supplement: elife-104725-supp1.xlsx › Supplementary_File_1b
Structural Complexity and Plasticity of Signaling Regulation at the Melanocortin-4 Receptor.
Kleinau G et al.
International Journal of Molecular Sciences, 2020
Signal Transduction and Pathogenic Modifications at the Melanocortin-4 Receptor: A Structural Perspective.
Heyder N et al.
Frontiers in Endocrinology, 2019
Structural and signaling requirements of the human melanocortin 4 receptor for MAP kinase activation.
Patten CS et al.
Regulatory Peptides, 2007
Molecular basis of melanocortin-4 receptor for AGRP inverse agonism.
Chen M et al.
Regulatory Peptides, 2006
Molecular determinants of ligand binding to the human melanocortin-4 receptor.
Yang YK et al.
Biochemistry, 2000
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