Varaico: Literature-Extracted Genetic Variants

Gene:MC4R
Variant:p.V255A
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MC4R

NM_005912.3:p.V255A

Associated Papers

High-resolution deep mutational scanning of the melanocortin-4 receptor enables target characterization for drug discovery.

Howard CJ et al.

Elife, 2025

40202051 (PubMed )
Supplement: elife-104725-supp1.xlsx › Supplementary_File_1b

MC4R Variants Modulate α-MSH and Setmelanotide Induced Cellular Signaling at Multiple Levels.

Rodríguez Rondón AV et al.

The Journal of Clinical Endocrinology and Metabolism, 2024

Heterozygous rare genetic variants in non-syndromic early-onset obesity.

Serra-Juhé C et al.

International Journal of Obesity (2005), 2020

30926952 (PubMed )
Supplement: 41366_2019_357_MOESM6_ESM.xlsx › Suppl_2_Controls_RSVs

Mutation-Induced Functional Alterations of CCR6.

Julian B et al.

The Journal of Pharmacology and Experimental Therapeutics, 2017

Pleiotropic functions of the transmembrane domain 6 of human melanocortin-4 receptor.

Huang H et al.

Journal of Molecular Endocrinology, 2012

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."