Associated Papers
SHU9119 and MBP10 are biased ligands at the human melanocortin-4 receptor.
Dai HC et al.
Biochemical Pharmacology, 2024
Alanine Scanning Mutagenesis of the DRYxxI Motif and Intracellular Loop 2 of Human Melanocortin-4 Receptor.
Yang LK et al.
International Journal of Molecular Sciences, 2020
Key amino acid residue in Melanocortin-1 receptor (melanocyte α-MSH receptor) for ligand selectivity.
Yang Y et al.
Molecular and Cellular Endocrinology, 2017
Peptide and small molecules rescue the functional activity and agonist potency of dysfunctional human melanocortin-4 receptor polymorphisms.
Xiang Z et al.
Biochemistry, 2007
Functional characterization of the modified melanocortin peptides responsible for ligand selectivity at the human melanocortin receptors.
Chen M et al.
Peptides, 2006
Molecular basis of melanocortin-4 receptor for AGRP inverse agonism.
Chen M et al.
Regulatory Peptides, 2006
Interactions of human melanocortin 4 receptor with nonpeptide and peptide agonists.
Pogozheva ID et al.
Biochemistry, 2005
Molecular determinants of human melanocortin-4 receptor responsible for antagonist SHU9119 selective activity.
Yang Y et al.
The Journal of Biological Chemistry, 2002
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