Varaico: Literature-Extracted Genetic Variants

Gene:MC4R
Variant:p.L44I
Back to variants list

MC4R

NM_005912.3:p.L44I

Associated Papers

Structural insights into ligand recognition and activation of the melanocortin-4 receptor.

Zhang H et al.

Cell Research, 2021

Structures of active melanocortin-4 receptor-Gs-protein complexes with NDP-α-MSH and setmelanotide.

Heyder NA et al.

Cell Research, 2021

34561620 (PubMed )
Supplement: 41422_2021_569_MOESM31_ESM.pdf

Functions of transmembrane domain 3 of human melanocortin-4 receptor.

Mo XL et al.

Journal of Molecular Endocrinology, 2012

Key amino acid residues in the melanocortin-4 receptor for nonpeptide THIQ specific binding and signaling.

Yang Y et al.

Regulatory Peptides, 2009

Contribution of the conserved amino acids of the melanocortin-4 receptor in [corrected] [Nle4,D-Phe7]-alpha-melanocyte-stimulating [corrected] hormone binding and signaling.

Chen M et al.

The Journal of Biological Chemistry, 2007

MTSEA prevents ligand binding to the human melanocortin-4 receptor by modification of cysteine 130 in transmembrane helix 3.

Cox A et al.

Febs Letters, 2005

Molecular determinants of ligand binding to the human melanocortin-4 receptor.

Yang YK et al.

Biochemistry, 2000

Select a paper to view details
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."