Associated Papers
Interplay between protein acetylation and ubiquitination controls MCL1 protein stability.
Shimizu K et al.
Cell Reports, 2021
Targeting FBW7 as a Strategy to Overcome Resistance to Targeted Therapy in Non-Small Cell Lung Cancer.
Ye M et al.
Cancer Research, 2017
Paxillin confers resistance to tyrosine kinase inhibitors in EGFR-mutant lung cancers via modulating BIM and Mcl-1 protein stability.
Wu DW et al.
Oncogene, 2016
Cyclin E/Cdk2-dependent phosphorylation of Mcl-1 determines its stability and cellular sensitivity to BH3 mimetics.
Choudhary GS et al.
Oncotarget, 2015
Serine 162, an essential residue for the mitochondrial localization, stability and anti-apoptotic function of Mcl-1.
Thomas LW et al.
Plos One, 2012
Thr 163 phosphorylation causes Mcl-1 stabilization when degradation is independent of the adjacent GSK3-targeted phosphodegron, promoting drug resistance in cancer.
Nifoussi SK et al.
Plos One, 2012
Sensitivity to antitubulin chemotherapeutics is regulated by MCL1 and FBW7.
Wertz IE et al.
Nature, 2011
Prevention of cytokine withdrawal-induced apoptosis by Mcl-1 requires interaction between Mcl-1 and Bim.
Jamil S et al.
Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire, 2010
Mcl-1 degradation during hepatocyte lipoapoptosis.
Masuoka HC et al.
The Journal of Biological Chemistry, 2009
Serine 64 phosphorylation enhances the antiapoptotic function of Mcl-1.
Kobayashi S et al.
The Journal of Biological Chemistry, 2007
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