Varaico: Literature-Extracted Genetic Variants

Gene:MCL1
Variant:p.S162A
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MCL1

NM_021960.5:p.S162A

Associated Papers

Serine 162, an essential residue for the mitochondrial localization, stability and anti-apoptotic function of Mcl-1.

Thomas LW et al.

Plos One, 2012

Thr 163 phosphorylation causes Mcl-1 stabilization when degradation is independent of the adjacent GSK3-targeted phosphodegron, promoting drug resistance in cancer.

Nifoussi SK et al.

Plos One, 2012

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."