Varaico: Literature-Extracted Genetic Variants

Gene:MDM2
Variant:p.S166A
Back to variants list

MDM2

NM_002392.6:p.S166A

Associated Papers

SUMO-specific protease SENP3 enhances MDM2-mediated ubiquitination of PARIS/ZNF746 in HeLa cells.

Nishida T

Biochemical and Biophysical Research Communications, 2022

MDM2's dual mRNA binding domains co-ordinate its oncogenic and tumour suppressor activities.

Gnanasundram SV et al.

Nucleic Acids Research, 2020

Chromatin-Bound MDM2 Regulates Serine Metabolism and Redox Homeostasis Independently of p53.

Riscal R et al.

Molecular Cell, 2016

MDM2 regulates hypoxic hypoxia-inducible factor 1α stability in an E3 ligase, proteasome, and PTEN-phosphatidylinositol 3-kinase-AKT-dependent manner.

Joshi S et al.

The Journal of Biological Chemistry, 2014

Sgk1 activates MDM2-dependent p53 degradation and affects cell proliferation, survival, and differentiation.

Amato R et al.

Journal of Molecular Medicine (berlin, Germany), 2009

HDM2 phosphorylation by MAPKAP kinase 2.

Weber HO et al.

Oncogene, 2005

Phosphorylation-dependent ubiquitylation and degradation of androgen receptor by Akt require Mdm2 E3 ligase.

Lin HK et al.

The Embo Journal, 2002

Select a paper to view details
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."