Varaico: Literature-Extracted Genetic Variants

Gene:MDM2
Variant:p.C213Y
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MDM2

NM_002392.6:p.C213Y

Associated Papers

Targeting the MDM2-p53 Interaction with Siremadlin: A Promising Therapeutic Strategy for Treating TP53 Wild-Type Chronic Lymphocytic Leukemia.

Aptullahoglu E et al.

Cancers, 2025

Splicing Modulation Results in Aberrant Isoforms and Protein Products of p53 Pathway Genes and the Sensitization of B Cells to Non-Genotoxic MDM2 Inhibition.

Aptullahoglu E et al.

International Journal of Molecular Sciences, 2023

36768733 (PubMed )
Supplement: ijms-24-02410-s001.zip › ijms-2135245-supplementary.pdf

The Yin and Yang of ERBB4: Tumor Suppressor and Oncoprotein.

Lucas LM et al.

Pharmacological Reviews, 2022

Germline TP53 mutational spectrum in French Canadians with breast cancer.

Arcand SL et al.

Bmc Medical Genetics, 2015

TP53 germline mutations in Portugal and genetic modifiers of age at cancer onset.

Pinto C et al.

Familial Cancer, 2009

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."