Varaico: Literature-Extracted Genetic Variants

Gene:MDM2
Variant:p.S394A
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MDM2

NM_002392.6:p.S394A

Associated Papers

Role of p53 in Regulating Radiation Responses.

Okazaki R

Life (basel, Switzerland), 2022

Allosteric changes in HDM2 by the ATM phosphomimetic S395D mutation: implications on HDM2 function.

Uhrik L et al.

The Biochemical Journal, 2019

Regulation of the Mdm2-p53 signaling axis in the DNA damage response and tumorigenesis.

Carr MI et al.

Translational Cancer Research, 2016

Intra molecular interactions in the regulation of p53 pathway.

Chen J

Translational Cancer Research, 2016

Mdm2 Phosphorylation Regulates Its Stability and Has Contrasting Effects on Oncogene and Radiation-Induced Tumorigenesis.

Carr MI et al.

Cell Reports, 2016

ATM phosphorylation of Mdm2 Ser394 regulates the amplitude and duration of the DNA damage response in mice.

Gannon HS et al.

Cancer Cell, 2012

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."